Literature Review: Pengaruh Nutritional Support Pada Kadar Albumin Pasien Intensive Care Unit (ICU).

Suharianto, Bella Palupi and Leny Budhi Harti, S.Gz., M.Si.Med., and Ayuningtyas Dian Ariestiningsih, S.Gz., M.P, . (2021) Literature Review: Pengaruh Nutritional Support Pada Kadar Albumin Pasien Intensive Care Unit (ICU). Sarjana thesis, Universitas Brawijaya.

Abstract

Pasien intensive care unit (ICU) mengalami peningkatan setiap tahunnya dan hampir semua pasien kritis mengalami anoreksia atau ketidakmampuan makan karena penurunan kesadaran sehingga asupan gizi diberikan berupa formula enteral maupun formula parenteral. Pasien ICU seringkali mengalami hipoalbuminemia yang disebabkan oleh pergeseran distribusi dari ruangan intravaskular ke interstitial, dan pelepasan hormon yang meningkatkan destruksi metabolisme albumin. Kadar albumin juga menjadi indikator adanya stres fisiologis dan status gizi. Tujuan penelitian ini adalah untuk mengetahui perbedaan kadar albumin pada pasien intensive care unit (ICU) yang mendapatkan nutritional support yaitu formula enteral, formula parenteral, serta kombinasi formula enteral parenteral. Penelitian ini merupakan literature review jenis narrative review, dengan mengumpulkan artikel melalui database yaitu PubMed secara online. Terdapat 4 artikel yang penelitiannya dilakukan di negara China, Turkey, dan Malaysia dari 220 artikel yang ditelaah sesuai kriteria inklusi yang ditetapkan dengan menggunakan protokol PRISMA. Hasil penelitian menunjukkan bahwa nutritional support yang dapat meningkatkan kadar albumin adalah formula enteral yang diperkaya oleh prebiotic fructo-oligosaccharides (FOS) dengan p <0,05 pada pasien neurokritis serta kombinasi formula enteral parenteral pada pasien pankreatitis akut dengan p <0,5 or p <,01 dan traumatis cedera otak dengan p <0,01. Formula parenteral kabiven dengan p <0,5 or p <0,1 dan penuh alimentasi dengan p <0,01 memiliki pengaruh menurunkan kadar albumin secara signifikan. Kesimpulan dari penelitian ini adalah kadar albumin pada pasien ICU dapat meningkat secara signifikan dengan diberikan formula enteral dengan penambahan prebiotic fructo-oligosaccharides dan kombinasi formula enteral parenteral dibandingkan pemberian formula standar atau formula parenteral.

English Abstract

Intensive care unit (ICU) patients increase every year and almost all critical patients have anorexia or an inability to eat because of decreased awareness so that nutritional intake is given by enteral formulas or parenteral formulas. ICU patients often sustain hypoalbuminemia caused by a friction in distribution from intravascular to interstitial, and the release hormones increase the destruction of albumin metabolism, besides that albumin levels are an indication of a physiological stress and as an indicator of nutritional status. It is possible to give enteral formulas, parenteral formulas, and a combination of enteral parenteral formulas can increase albumin levels. The purpose of this study was to determine differences in albumin levels in intensive care unit (ICU) patients who received nutritional support, namely enteral formulas, parenteral formulas, and combination of enteral parenteral formulas. This research is a literature review type of narrative review, by collecting articles through an online database, namely PubMed. There were 4 articles whose research was carried out in China, Turkey, and Malaysia from 220 articles that were reviewed according to the inclusion criteria established using the PRISMA. The results showed that nutritional support which can increase albumin levels is enteral formula enriched by prebiotic fructo-oligosaccharides (FOS) with p<0,05 for neurocritical care patients and a combination of enteral parenteral formulas with p <0,5 or p <0,1 for severe acute pancreatitis and traumatic brain injury with p <0,01. The parenteral formula of kabiven with p <0,5 or p <0,1 and full of alimentation with p <0,01 has the effect of reducing albumin levels significantly. The conclusion of this study is the level of albumin in ICU patients can increase significantly with enteral formula enriched by prebiotic fructooligosaccharides (FOS) and combination formulas be compared standar formula or parenteral formula.

Item Type:	Thesis (Sarjana)
Identification Number:	0521060108
Uncontrolled Keywords:	kadar albumin, ICU, nutritional support. albumin content, ICU, nutritional support.
Subjects:	600 Technology (Applied sciences) > 613 Personal health and safety
Divisions:	Fakultas Kedokteran > Ilmu Gizi
Depositing User:	Budi Wahyono Wahyono
Date Deposited:	30 Nov 2021 06:50
Last Modified:	25 Feb 2022 01:34
URI:	http://repository.ub.ac.id/id/eprint/186865

Text (DALAM MASA EMBARGO) - Bella Palupi Suharianto.pdf Restricted to Registered users only until 31 December 2023. Download (1MB)

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