Yuliani, Kartika (2015) Analisis Massa White Adipose Tissue (WAT) pada Tikus Rattus novergicus Galur Wistar Jantan yang Diberi Diet Aterogenik Modifikasi Standard AIN-93M dan Diet Normal Standard AIN-93M. Sarjana thesis, Universitas Brawijaya.
Abstract
Aterosklerosis atau pengerasan arteri merupakan kejadian yang sering diawali dengan kondisi dislipidemia dan obesitas. Obesitas pada umumnya terjadi akibat penumpukan triasil gliserol dalam white adipose tissue (WAT) sebagai akibat kelebihan intake energi. Pembentukan aterosklerosis dapat dipicu melalui pemberian diet aterogenik yang dapat dimodifikasi dari diet standard. Penelitian ini bertujuan untuk mengetahui perbedaan massa WAT pada tikus Rattus novergicus galur wistar jantan yang diberi diet aterogenik modifikasi standard AIN-93 M dan diet normal standard AIN-93M. Penelitian eksperimental ini menggunakan randomized post test control group design dengan pengambilan sampel menggunakan Rancangan Acak Lengkap (RAL) untuk membagi sampel menjadi 2 kelompok, yaitu P1 “diet aterogenik” dan P2 “diet normal”. Variabel yang diukur yakni WAT diambil dari bagian omental, perirenal, inguinal dan epididimal. Hasil penelitian menunjukkan bahwa rata-rata intake pakan dan intake lemak pada P1 lebih tinggi daripada P2 (p=0,006 dan p=0,001). Namun, tidak ada perbedaan pada berat badan tikus akhir. Total massa WAT P1=3,87 gram dan P2= 2,59 gram (p=0,001). Kesimpulan dari penelitian ini adalah ada perbedaan jumlah white adipose tissue (WAT) pada tikus Rattus novergicus galur wistar jantan yang diberi diet aterogenik modifikasi standard AIN-93 M dan diet normal standard AIN-93M.
English Abstract
Atheroschlerosis or hardening of arteries is happening from dyslipdaemia and obessity. The obessity is a result of accumulation of triasilgriserol as effect of excessive energy intake. The forming of athresclerosis needs an atherogenic diet that can modified from standard diet. This research is aimed to know the difference of WAT mass on Male Rat (Rattus novergicus strain Wistar) after giving of atherogenic diet modified from AIN-93M standard and normal standard AIN-93M diet. This experimental study using randomized post test control group design as research design and using random sampling to select the samples then divide it into two groups. The groups are P1 “atherogenic diet” and P2 “normal diet”. Variable measured is WAT that taken from omental, perirenal, inguinal and epididymal sections. Result of this research show that averages of dietary food intake and dietary fat intake on P1 are higher than P2 (p=0,006 and p=0,001). However, the final body weight isn’t significantly difference. WAT total mass on P1=3,87 gram and P2= 2,59 gram (p=0,001). The conclusion is there is a difference of white adipose tissue (WAT) mass on Male Rat (Rattus novergicus strain Wistar) after giving of atherogenic diet modified from AIN-93M standard and normal standard AIN-93M diet.
| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | SKR/FK/2015/598/051504592 |
| Subjects: | 600 Technology (Applied sciences) > 613 Personal health and safety > 613.2 Dietetics |
| Divisions: | Fakultas Kedokteran > Ilmu Gizi |
| Depositing User: | Endang Susworini |
| Date Deposited: | 24 Aug 2015 14:22 |
| Last Modified: | 19 Oct 2021 08:29 |
| URI: | http://repository.ub.ac.id/id/eprint/125384 |
Preview |
Text
5_ABSTRAK_ENG.pdf Download (1MB) | Preview |
Preview |
Text
6_DAFTAR_ISI.pdf Download (1MB) | Preview |
Preview |
Text
4_ABSTRAK.pdf Download (1MB) | Preview |
Preview |
Text
3_KATA_PENGANTAR.pdf Download (1MB) | Preview |
Preview |
Text
7_DAFTAR_TABEL.pdf Download (1MB) | Preview |
Preview |
Text
8_DAFTAR_GAMBAR.pdf Download (1MB) | Preview |
Preview |
Text
9_DAFTAR_LAMPIRAN.pdf Download (1MB) | Preview |
Preview |
Text
10_DAFTAR_SINGKATAN.pdf Download (1MB) | Preview |
Preview |
Text
13_BAB_III.pdf Download (1MB) | Preview |
Preview |
Text
14_BAB_IV.pdf Download (1MB) | Preview |
Preview |
Text
12_BAB_II.pdf Download (1MB) | Preview |
Preview |
Text
11_BAB_I.pdf Download (1MB) | Preview |
Preview |
Text
15_BAB_V.pdf Download (1MB) | Preview |
Preview |
Text
17_BAB_VII.pdf Download (1MB) | Preview |
Preview |
Text
16_BAB_VI.pdf Download (1MB) | Preview |
Preview |
Text
18_DAFTAR_PUSTAKA.pdf Download (1MB) | Preview |
Preview |
Text
1_COVER.pdf Download (1MB) | Preview |
Preview |
Text
2_LEMBAR_PENGESAHAN.pdf Download (2MB) | Preview |
Actions (login required)
 |
View Item |