Hasana, SitiSofiatul (2015) Perbedaan Jumlah Foam Cell Pada Tikus Rattus Norvegicus Galur Wistar Jantan Yang Diberi Diet Aterogenik Modifikasi Standar Ain-93m Dan Diet Normal Standar Ain-93m (Studi Pembuatan Modifikasi Pakan Tik. Sarjana thesis, Universitas Brawijaya.
Abstract
Aterosklerosis Merupakan Penyakit Kronik Yang Kompleks Akibat Adanya Penumpukan Lemak Pada Dinding Pembuluh Darah. Penumpukan Total Kolesterol Dan Ldl Dalam Jangka Waktu Lama Dapat Membentuk Plak Atau Sel Busa (Foam Cell). Pada Suatu Penelitian Untuk Membentuk Suatu Kondisi Aterosklerosis Diperlukan Diet Aterogenik Modifikasi Standar Ain-93m Yang Merupakan High Fat Diet Modifikasi Ain-93m Dengan Penambahan Asam Kolat Dan Kolesterol. Penelitian Ini Bertujuan Untuk Mengetahui Perbedaan Antara Pemberian Diet Aterogenik Modifikasi Standar Ain-93m Dengan Diet Normal Standar Ain-93m Terhadap Jumlah Foam Cell Pada Aorta Tikus Rattus Norvegicus Strain Wistar Jantan. Penelitian Ini Menggunakan True Experimental Laboratory Dengan Metode Randomized Control Group Postest Design Dengan Menggunakan Tikus Rattus Novergicus Galur Wistar Jantan. Pemilihan Sampel Dilakukan Menggunakan Metode Ral (Rancangan Acak Lengkap) Dengan Jumlah Sampel Total Sebanyak 32 Tikus. Uji Statistik Menggunakan Independent T Test. Hasil Penelitian Menunjukan Kelompok Diet Normal Standar Ain-93m (P2) Dengan Rata-Rata Asupan 10,47 ± 1.45, Energi 33,5 ± 4,65 Kkal Dapat Membentuk Jumlah Foam Cell 1,6 ± 0,33, Sedangkan Kelompok Diet Aterogenik Modifikasi Standar Ain-93m (P2) Dengan Rata-Rata Asupan 8,73 ± 1,94 Gram, Energi 36,5 ± 8,12 Kkal Dapat Membentuk Jumlah Foam Cell 3,1 ± 0,38. Berdasarkan Penelitian Ini Dapat Disimpulkan Ada Perbedaan Yang Signifikan Jumlah Foam Cell Aorta Tikus Rattus Norvegicus Strain Wistar Jantan Yang Diberi Diet Aterogenik Modifikasi Standar Ain-93m Dan Diberi Diet Normal Standar Ain-93m.
English Abstract
Atherosclerosis Is A Complex Chronic Disease Characterized By The Accumulation Of Lipids Within Arterial Walls. Stacking Of Total Cholesterol And Ldl In The Long Term Could Form Plaques Or Foam Cells. Atherogenic Diet Standard Ain-93m Modification As A High Fat Diet Modified From Standard Diet Ain-93m With The Addition Of Cholic Acid And Cholesterol Is Necessarily Needed To Establish An Atherogenic Condition. This Study Aimed To Determine The Difference Between The Administration Of Atherogenic Diet Standard Ain-93m Modification With A Normal Standard Diet Of Ain-93m To The Number Of Foam Cells Formed In The Aorta Of Male Rattus Norvegicus Strain Wistar Rats. This Study Used A True Experimental Laboratoric With Control Group Post Test Design Using Male Rattus Norvegicus Strain Wistar Rats. Sampling Was Carried Out By Completely Random Sampling With 32 Rats For Total Sample. The Result Tested Statistically Using Independent T-Test. Results Showed Normal Ain Group (P2) With An Average Intake Of 10,47 ± 1.45 G, Energy 33,5 ± 4,65 Kcal Formed Foam Cells With The Number Of 1,6 ± 0,33, Meanwhile Atherogenic Ain With An Average Intake Of 8,73 ± 1,94g , Energy 36,5 ± 8,12 Kcal Formed Foam Cells With The Number Of 3,1 ± 0,38. Based On This Study, It Can Be Concluded That There Are Significant Differences In The Number Of Foam Cells Of Aortic Rats Fed With Atherogenic Diet Standard Ain – 93m Modification And Normal Diet Standard Ain – 93m.
| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | SKR/FK/2015/382/051503203 |
| Subjects: | 600 Technology (Applied sciences) > 613 Personal health and safety > 613.2 Dietetics |
| Divisions: | Fakultas Kedokteran > Ilmu Gizi |
| Depositing User: | Budi Wahyono Wahyono |
| Date Deposited: | 11 May 2015 09:37 |
| Last Modified: | 19 Oct 2021 02:05 |
| URI: | http://repository.ub.ac.id/id/eprint/125148 |
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