Pratama, Adhya Aji and dr. Perdana Aditya Rahman,, SpPD, K-R and Dr. dr. Cesarius Singgih Wahono,, SpPD, K-R (2024) Perbedaan Karakteristik Penyintas COVID-19 Kronik dengan dan Tanpa Keluhan Muskuloskeletal. Magister thesis, Universitas Brawijaya.
Abstract
Penyintas COVID-19 kronik adalah pasien yang muncul manifestasi lebih dari 12 minggu pasca infeksi. Beberapa gejala yang sering muncul dari keluhan muskuloskeletal antara lain kaku sendi dan nyeri sendi. Pada penelitian ini akan dibahas terkait penyintas COVID-19 kronik dengan dan tanpa keluhan muskuloskeletal. Tujuan: Tujuan utama adalah untuk mengetahui perbedaan karakteristik pada penyintas COVID-19 kronik dengan dan tanpa keluhan muskuloskeletal dalam hal demografi, komorbiditas, dan data laboratorium. Metode: Didapatkan respon dari 83 penyintas COVID-19 yang dirawat di RS Saiful Anwar Malang antara Mei 2021 hingga Agustus 2023. Penelitian ini bersifat retrospektif dan analitik. Skoring yang digunakan menggunakan GALS (Gait, Arm, Legs and Spine) karakteristik pasien kami ambil sebagai data primer melalui google form. Sementara data sekunder diambil dari rekam medis. Hasil: Dari 83 penyintas COVID-19 kronik, 34 orang (40,9%) mengalami keluhan muskuloskeletal, seperti kaku dan nyeri sendi. Analisis menunjukkan perbedaan signifikan antara derajat keparahan sedang dengan adanya keluhan muskuloskeletal (p = 0,00), di mana pasien dengan keparahan sedang lebih sering mengalami keluhan tersebut. Dari hasil laboratorium, ditemukan bahwa kadar trombosit (p = 0,0), CRP (p = 0,03), dan D-Dimer (p < 0,00) lebih tinggi pada penyintas tanpa keluhan muskuloskeletal dibandingkan dengan yang mengalami keluhan. Kesimpulan: Didapatkan adanya perbedaan derajat keparahan sedang penyintas COVID-19 kronik dengan dan tanpa keluhan muskuloskeletal (keluhan muskuloskeletal lebih banyak). Didapatkan perbedaan rerata kadar trombosit, CRP dan D-Dimer pada penyintas COVID-19 kronik dengan dan tanpa keluhan muskuloskeletal (tanpa keluhan muskuloskeletal lebih banyak).
English Abstract
BACKGROUND: Chronic COVID-19 survivors are patients who have manifestations more than 12 weeks after infection. Some of the symptoms that often arise from musculoskeletal complaints includes joint stiffness and joint pain. This study will discuss chronic COVID-19 survivors with and without musculoskeletal complaints. OBJECTIVE: The main objective is to evaluate differences in characteristics of chronic COVID-19 survivors with and without musculoskeletal complaints in terms of demographics, comorbidities, and laboratory data. METHODS: Responses were obtained from 83 COVID-19 survivors who were treated at Saiful Anwar Hospital Malang between May 2021 and August 2023. This study was retrospective and analytic. The scoring used used GALS (Gait, Arm, Legs and Spine) patient characteristics we took as primary data through google form. Secondary data was taken from medical records. RESULTS: Among 83 chronic COVID-19 survivors, 34 people (40.9%) reported musculoskeletal complaints such as stiffness and joint pain. The analysis indicated a significant correlation between moderate disease severity and the presence of musculoskeletal complaints (p = 0.00), with patients experiencing moderate severity more likely to report these complaints. Additionally, laboratory findings showed that survivors without musculoskeletal complaints had higher platelet (p = 0.02), CRP (p = 0.03), and D-dimer (p < 0.00) levels compared to those with musculoskeletal complaints. CONCLUSION: There is a difference among chronic COVID-19 survivors with moderate severity regarding the presence of musculoskeletal complaints (musculoskeletal complaints are more frequent). Mean differences of platelets, CRP, and D-Dimer levels were also found between chronic COVID-19 survivors with and without musculoskeletal complaints (without musculoskeletal complaints are more frequent).
| Item Type: | Thesis (Magister) |
|---|---|
| Identification Number: | 0424060144 |
| Uncontrolled Keywords: | CRP, D-Dimer, GALS (Gait, Arm, Legs and Spine), keluhan muskuloskeletal, penyintas COVID-19 kronik. |
| Divisions: | Profesi Kedokteran > Spesialis Ilmu Penyakit Dalam, Fakultas Kedokteran |
| Depositing User: | Unnamed user with username nova |
| Date Deposited: | 13 Jan 2025 01:11 |
| Last Modified: | 13 Jan 2025 01:11 |
| URI: | http://repository.ub.ac.id/id/eprint/234553 |
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