Khoirunnisa, Rani Luthfiah and Yuliana Ratna Kumala, drg., Sp.KG (2022) “Efektivitas Antibakteri Ekstrak Etanol Buah Anggur Merah (Vitis vinifera varian Red globe) sebagai bahan irigasi Saluran Akar Terhadap Pertumbuhan Bakteri Actinomyces spp secara In Vitro”,. Sarjana thesis, Universitas Brawijaya.
Abstract
Bakteri Actinomyces spp merupakan salah satu bakteri yang dapat menyebabkan kegagalan saluran akar. Banyak bahan antibakteri yang telah digunakan untuk membunuh bakteri Actinomyces spp, salah satunya yaitu buah anggur (Vitis vinifera varian Red globe) karena memiliki senyawa aktif antibakteri yaitu flavonoid, asam fenolat dan tanin. Tujuan: Mengetahui efektivitas antibakteri ekstrak etanol buah anggur (Vitis vinifera varian Red globe) sebagai bahan irigasi saluran akar terhadap pertumbuhan bakteri Actinomyces spp secara in vitro. Metode: Penelitian true experimental menggunakan metode dilusi cair dengan 8 sampel yang terdiri dari K(-), K(+), 25%, 22,5%, 20%, 17,5%, 15%, dan 12,5%. Analisis statistik menggunakan uji Kruskal Wallis. Hasil: Kadar Bunuh Minimum (KBM) pada konsentrasi 15%. Hasil uji statistika menunjukkan terdapat perbedaan signifikan pengaruh pemberian ekstrak etanol buah anggur (Vitis vinifera varian Red globe) pada masing-masing konsentrasi dalam menghambat pertumbuhan bakteri Actinomyces spp. Kesimpulan: Ekstrak etanol buah anggur (Vitis vinifera varian Red globe) memiliki efektivitas antibakteri sebagai bahan irigasi saluran akar terhadap pertumbuhan bakteri Actinomyces spp in vitro.
English Abstract
Actinomyces spp. is a bacterium that can cause root canal failure. Many antibacterial materials have been used to kill Actinomyces spp. bacteria, one of which is grapes (Vitis vinifera variant Red globe) because they have antibacterial active compounds, namely flavonoids, phenolic acids and tannins. Objective: To determine the antibacterial effectiveness of ethanolic extract of grapes (Vitis vinifera variant Red globe) as a root canal irrigation agent against the growth of Actinomyces spp. bacteria in vitro. Methods: True experimental research using the dilution method with 8 sample groups consisting of K(-), K(+), 25%, 22,5%, 20%, 17,5%, 15%, dan 12,5%. Statistical analysis using Kruskal Wallis test. Results: Minimum Bactericidal Concentration (MBC) at a concentration of 15%. The results of statistical tests showed that there were significant differences in the effect of ethanol extract of grapes (Vitis vinifera variant Red globe) at each concentration in inhibiting the growth of Actinomyces spp. Conclusion: In this study, the ethanolic extract of grapes (Vitis vinifera) has antibacterial effectiveness as a root canal irrigation agent against the growth of Actinomyces spp. bacteria in vitro.
| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | 052206 |
| Uncontrolled Keywords: | Ekstrak etanol buah anggur, Actinomyces spp, kadar bunuh minimum |
| Divisions: | Fakultas Kedokteran > Pendidikan Dokter |
| Depositing User: | Unnamed user with username nova |
| Date Deposited: | 20 Nov 2024 06:01 |
| Last Modified: | 20 Nov 2024 06:01 |
| URI: | http://repository.ub.ac.id/id/eprint/232849 |
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