Hainuddin, dr. Naufal Akbar Nur and dr. Ungky Agus Setyawan, Sp.P(K) and dr. Rezki Tantular, Sp.P(K) and dr. Deden Permana, Sp.P(K) (2024) Hubungan Kualitas Hidup Pasien Kanker Paru Dengan Neutrofil Limfosit Ratio Dan Uji Jalan Enam Menit. Magister thesis, Universitas Brawijaya.
Abstract
Mortalitas dan morbiditas akibat kanker paru masih tinggi dan terus meningkat, hal ini berhubungan kualitas hidup sehingga perlu diperhatikan keluhan, kondisi fisik, emosional maupun sosial. Pemeriksaan Neutrophil Lymphocyte Ratio (NLR), performance status dan uji jalan enam menit (six minutes walking test/ 6MWT) digunakan assessment tools kualitas hidup pasien. Pada penelitian ini melihat hubungan antara kualitas hidup pasien kanker paru dengan NLR dan 6MWT. Metode : Desain penelitian observasional analitik cross sectional pada 45 pasien kanker paru yang melakukan pengisian kuisioner The Functional Assessment of Cancer Therapy-Lung (FACT-L) untuk menilai kualitas hidup, pemeriksaan NLR dan 6MWT. Selanjutnya dianalisis menggunakan chisquare untuk membedakan dua kategorik dan analisis korelasi menggunakan spearman. Hasil: Hasil ROC pada kuisioner FACT-L cut off point 76, dengan 12 pasien (26.7%) kualitas hidup buruk dan 33 pasien (73.3%) baik. Pada analisis kualitas hidup dengan NLR hasil tidak berhubungan secara signifikan dengan nilai koefisien korelasi 0.019 (p = 0.899), namun terdapat hubungan signifikan antara kualitas hidup dengan 6MWT dengan nilai koefisien korelasi 0.470 (p = 0.001). Kesimpulan: Kualitas hidup pasien kanker paru dapat dilihat dari 6MWT bukan dari NLR hal ini disebabkan banyak faktor yang mempengaruhi seperti stadium, komorbid dan terapi yang diberikan.
English Abstract
Mortality and morbidity due to lung cancer is still high and continues to increase, this is related to quality of life so it is necessary to pay attention to complaints, physical, emotional and social conditions. Neutrophil Lymphocyte Ratio (NLR), performance status and six minute walking test (6MWT) are used as assessment tools for the patient's quality of life. In this study, we looked at the relationship between the quality of life of lung cancer patients and NLR and 6MWT. Methods: Cross sectional observational analytical study design on 45 lung cancer patients who completed the Functional Assessment of Cancer Therapy-Lung (FACT-L) questionnaire to assess quality of life, NLR and 6MWT examinations. Next, it was analyzed using chisquare to differentiate the two categories and correlation analysis using Spearman. Results: ROC results on the FACT-L questionnaire cut off point 76, with 12 patients (26.7%) poor quality of life and 33 patients (73.3%) good. In the analysis of quality of life with NLR, the results were not significantly related with a correlation coefficient value of 0.019 (p = 0.899), but there was a significant relationship between quality of life and 6MWT with a correlation coefficient value of 0.470 (p = 0.001). Conclusion: The quality of life of lung cancer patients can be seen from 6MWT, not NLR, this is due to many influencing factors such as stage, comorbidities and therapy given.
| Item Type: | Thesis (Magister) |
|---|---|
| Identification Number: | 0424060040 |
| Uncontrolled Keywords: | Kanker Paru, Kualitas Hidup, NLR, 6MWT |
| Divisions: | Profesi Kedokteran > Spesialis Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran |
| Depositing User: | Unnamed user with username nova |
| Date Deposited: | 16 Jul 2024 07:09 |
| Last Modified: | 16 Jul 2024 07:09 |
| URI: | http://repository.ub.ac.id/id/eprint/223571 |
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