Purnomo, Indrawan Tri and dr. Rodhiyan Rakhmatiar, Sp.S (K), FINA, M. Biomed and Dr. dr. Shahdevi Nandar Kurniawan, Sp.S (K) and dr. Harun Al Rasyid, MPH (2024) Hubungan antara Skor MoCA Ina dan Faktor Demografi dengan Skala Fazekas pada Pasien Pasca Stroke Trombosis dengan Gangguan Kognitif di RS dr. Saiful Anwar Jawa Timur. Magister thesis, Universitas Brawijaya.
Abstract
Latar Belakang : Sampai saat ini stroke menjadi salah satu penyebab kematian tertinggi di dunia. Pada pasien stroke terjadi kerusakan beberapa sel neuron yang dapat mengakibatkan gangguan fungsi sensoris, fungsi motoris dan fungsi kognitif sehingga dapat mempengaruhi kualitas hidup dan kemampuan bekerja. Namun berdasarkan prospektif yang ada, masih menjadi perdebatan apakah efek kognitif akibat langsung dari stroke atau terkait usia. Evaluasi fungsi kognitif ini sangat dibutuhkan untuk menentukan tingkat kemampuan fungsional yang dapat mempengaruhi penanganan secara tepat dan prognosis kedepannya. Tujuan Penelitian : Penelitian ini bertujuan untuk mengetahui hubungan antara skor MoCA Ina dan faktor demografi dengan skala Fazekas pada pasien pasca stroke trombosis dengan gangguan kognitif di RS dr. Saiful Anwar Jawa Timur. Metode dan Sampel Penelitian : Penelitian cross-sectional study dengan mengambil data sekunder dari rekam medis pasien pasca stroke trombosis dengan gangguan kognitif berjumlah 51 responden yang diambil di Poli Memori RS dr. Saiful Anwar Jawa Timur pada bulan Agustus 2020 - Desember 2022 yang memenuhi kriteria inklusi dan eksklusi. Skoring MoCA Ina dan hasil MRI kepala dimasukkan dalam populasi sampel lalu dikelompokkan berdasarkan skala fazekas yang nantinya akan dinilai korelasinya dengan uji Fisher. Hasil Penelitian: Berdasarkan sampel yang diperoleh didapatkan karakteristik 62.7% (32 orang) berjenis kelamin laki-laki, kelompok usia didapatkan 78.4% (40 orang) berusia >50 tahun, 49% (25 orang) dalam kategori fazekas Grade III, serta sebanyak 52.9% (27 orang) didiagnosis Demensia Vascular + Riwayat Stroke. Penghitungan statistik yang dilakukan dengan uji Fisher berdasarkan usia didapatkan nilai p sebesar 0.027 (p<0.05) | OR (95% CI)=5.833 (1.286- 26.453). Berdasarkan jenis kelamin didapatkan p value sebesar 0.725 (>0.05) | OR (95% CI)=1.493 (0.336-6.633). Hasil uji fisher berdasarkan hubungan antara skala fazekas dengan skor MoCA Ina pada pasien pasca stroke dengan gangguan kognitif didapatkan p value sebesar 0.010 (<0.05) | OR (95% CI)= 0.077 (0.011-0.516). Uji Fisher dengan p-value <0.05 dianggap bermakna secara statistik. Kesimpulan : Terdapat korelasi negatif antara skor MoCA Ina dan skala Fazekas pada pasien pasca stroke dengan gangguan kognitif. Pada penelitian ini juga didapatkan hubungan antara skala Fazekas dan usia pada pasien pasca stroke dengan gangguan kognitif. Evaluasi skala fazekas pada MRI kepala perlu dilakukan karena dapat membantu memprediksi penurunan fungsi kognitif, sehingga dapat dilakukan terapi dini dan rehabillitasi dengan tepat.
English Abstract
Background: Until now stroke is one of the highest causes of death in the world. In stroke patients there is damage to several neuron cells which can result in impaired sensory function, motor function and cognitive function so that it can affect quality of life and ability to work. However, based on existing prospective studies, it is still debatable whether cognitive effects are a direct result of stroke or age-related. Evaluation of cognitive function is needed to determine the level of functional ability that can affect appropriate treatment and future prognosis. Research Objective: This study aims to determine the relationship between MoCA Ina scores and demographic factors with the Fazekas scale in post-stroke thrombosis patients with cognitive impairment at Dr. Saiful Anwar Hospital, East Java. Research Methods and Samples: Cross-sectional study research by taking secondary data from medical records of post-stroke thrombosis patients with cognitive impairment totaling 51 respondents taken at the Memory Poly of Dr. Saiful Anwar East Java Hospital in August 2020 - December 2022 who met the inclusion and exclusion criteria. MoCA Ina scoring and head MRI results were included in the sample population and then grouped based on the fazekas scale which will later be assessed for correlation with the Fisher test. Results: Based on the sample obtained, 62.7% (32 people) were male, 78.4% (40 people) were >50 years old, 49% (25 people) were in the Grade III fazekas category, and 52.9% (27 people) were diagnosed with Vascular Dementia + History of Stroke. Statistical calculations performed with the Fisher test based on age obtained a p value of 0.027 (p <0.05) | OR (95% CI)=5.833 (1.286-26.453). Based on gender, the p value was 0.725 (>0.05) | OR (95% CI)=1.493 (0.336- 6.633). Fisher test results based on the relationship between the fazekas scale and the MoCA Ina score in post-stroke patients with cognitive impairment obtained a p value of 0.010 (<0.05) | OR (95% CI) = 0.077 (0.011-0.516). Fisher's test with p-value <0.05 is considered statistically significant. Conclusion: There is a negative correlation between MoCA Ina score and Fazekas scale in post-stroke patients with cognitive impairment. This study also found a relationship between the Fazekas scale and age in post-stroke patients with cognitive impairment. Evaluation of the Fazekas scale on head MRI needs to be done because it can help predict the decline in cognitive function, so that early therapy and rehabillitation can be done appropriately.
| Item Type: | Thesis (Magister) |
|---|---|
| Identification Number: | 042406 |
| Uncontrolled Keywords: | Stroke trombosis, gangguan kognitif, skor MoCA Ina, skala fazekas-Stroke thrombosis, cognitive impairment, MoCA Ina score, Fazekas scale |
| Divisions: | Profesi Kedokteran > Spesialis Neurologi, Fakultas Kedokteran |
| Depositing User: | Sugeng Moelyono |
| Date Deposited: | 01 Aug 2024 07:28 |
| Last Modified: | 01 Aug 2024 07:28 |
| URI: | http://repository.ub.ac.id/id/eprint/223374 |
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