Putri Kusumajati, Anindya and dr. Hidayat Sujuti, Sp.M(K), Ph.D and dr. T. Budi Sulistya, Sp.M(K) (2024) Perbandingan Penggunaan Ophthalmic Viscosurgical Device (Ovd) Kohesif Dan Teknik Soft Shell Terhadap Densitas Dan Koefisien Variasi Sel Endotel Kornea Pada Fakoemulsifikasi. Magister thesis, Universitas Brawijaya.
Abstract
TUJUAN Studi yang menggunakan hydroxypropyl-methylcellulose (HPMC) sebagai agen dispersif ophthalmic viscosurgical device (OVD) pada soft shell teknik sangat terbatas. Studi ini membandingkan OVD kohesif dan teknik soft shell (natrium hyaluronat and HPMC) terhadap densitas dan koefisien variasi sel endotel kornea pada fakoemulsifikasi. METODE Studi ini merupakan kohort retrospektif yang menggunakan rekam medis, dan dilakukan di kota Malang, sejak Maret hingga September 2022. Densitas dan koefisien viariasi endotel kornea diukur pada saat pre-operasi, 1 hari dan 1 bulan paska operasi, lalu dilakukan uji statistik Mann-Whitney untuk menilai perbedaan antara dua kelompok. HASIL Didapatkan 68 rekam medis pasien yang memenuhi kriteria inklusi. Terdapat perbedaan signifikan pada densitas endotel 1 hari paska operasi (p 0.021) dan 1 bulan paska operasi (p 0.016), dan penurunan densitas endotel lebih rendah pada teknik soft shell. Tidak didapatkan perbedaan signifikan pada koefisien variasi sel diantara 2 kelompok pada pre-operasi, 1 hari dan 1 bulan paska operasi. KESIMPULAN Penggunaan teknik OVD akan mempengaruhi densitas endotel kornea setelah fakoemulsifikasi. Penurunan densitas lenih rendah pada teknik soft shell (natrium hyaluronat and HPMC).
English Abstract
OBJECTIVE There are few studies using hydroxypropyl-methylcellulose (HPMC) as dispersive ophthalmic viscosurgical device (OVD) in the soft shell technique. We compare cohesive-only OVD and softshell technique (natrium hyaluronate and HPMC) on density and coefficient of variation of corneal endothelial cells in phacoemulsification. METHODS Observational retrospective cohort study conducted in Malang, from March to September 2022 by using medical records. Density and coefficient of variation of corneal endothelial were recorded pre-operative, 1 day, and 1 month after surgery and then compared between 2 groups. Analysis was performed by MannWhitney. RESULTS A total of 68 patients’ medical records were collected. There was a significant difference in endothelial density 1 day(p 0.021) and 1 month after surgery(p 0.016), and the decrease in endothelial density was lower in the softshell technique. There was no significant increase in the coefficient of variation between the 2 groups on pre-operative, 1 day, and 1 month after surgery. CONCLUSIONS The use of OVD technique affects corneal endothelial density after phacoemulsification. Decreasing endothelial density was lower in the softshell technique (natrium hyaluronate and HPMC).
| Item Type: | Thesis (Magister) |
|---|---|
| Identification Number: | 0424060014 |
| Divisions: | Profesi Kedokteran > Spesialis Ilmu Kesehatan Mata, Fakultas Kedokteran |
| Depositing User: | Unnamed user with username nova |
| Date Deposited: | 13 Jun 2024 06:54 |
| Last Modified: | 13 Jun 2024 06:54 |
| URI: | http://repository.ub.ac.id/id/eprint/219998 |
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