Cesa, Neysa Ardrasheila and dr. Novi Khila Firani, M.Kes, Sp.PK, and dr. Ery Olivianto, SpA(K) (2024) Korelasi antara Kadar Limfosit, Monosit, dan Lymphocyte to Monocyte Ratio (LMR) dengan Derajat Keparahan Pneumonia Anak. Sarjana thesis, Universitas Brawijaya.
Abstract
Pneumonia menjadi penyebab utama kematian anak berusia kurang dari 5 tahun. Penentuan derajat keparahan pneumonia anak biasanya hanya berdasarkan gambaran klinis dan pemeriksaan fisik, sehingga terkadang sulit untuk membedakan tingkat keparahan pneumonia apabila gejala klinis tidak begitu jelas. Padahal, ketepatan dalam menentukan derajat pneumonia sangat penting untuk menentukan terapi dan mencegah prognosis yang lebih buruk. Limfosit dan monosit merupakan indikator yang digunakan untuk mengetahui status kekebalan tubuh manusia dan mendeteksi inflamasi, serta pemeriksaan laboratorium yang mudah diukur, dikerjakan, dan rutin dilakukan di fasilitas kesehatan primer. Penelitian ini dilakukan untuk mengetahui korelasi antara kadar limfosit, monosit, dan lymphocyte-to-monocyte ratio (LMR) dengan derajat keparahan pneumonia anak. Penelitian ini merupakan penelitian retrospektif dengan desain cross-sectional. Data diperoleh dari rekam medis pasien terdiagnosis pneumonia berusia 2 hingga 60 bulan di RSUD dr. Saiful Anwar Malang. Hasil penelitian ini ditemukan bahwa tidak terdapat korelasi limfosit (p=0,427; r=0,094) dan monosit (p=0,274, r=0,130) dengan derajat keparahan pneumonia, serta terdapat korelasi dengan koefisien korelasi lemah antara LMR (p=0.019, r=-0,275) dengan derajat keparahan pneumonia. Kesimpulan dari penelitian ini adalah LMR berkorelasi negatif lemah dengan derajat keparahan pneumonia anak.
English Abstract
Pneumonia has become the main cause of death in children under 5 years old. The determination of the severity of childhood pneumonia is usually based on clinical presentations and physical examinations, which makes it sometimes challenging to distinguish the severity levels when clinical symptoms are not very clear. However, precision in determining the degree of pneumonia is important for prescribing appropriate therapy and preventing a worse prognosis. Lymphocytes and monocytes serve as indicators used to assess the immune status of the human body and detect inflammation, and the laboratory examination is easily measured, performed, and routinely conducted in primary healthcare facilities. Therefore, this study aims to determine the correlation between lymphocyte levels, monocyte levels, and the lymphocyte-to-monocyte ratio (LMR) with the severity of childhood pneumonia. This is a retrospective study using a cross-sectional method, which utilizes secondary data from the medical records of patients diagnosed with pneumonia aged 2 to 60 months who were treated at the RSUD dr. Saiful Anwar Malang. Based on the study’s results, it was found that there was no correlation between lymphocytes (p=0.427; r=0.094) and monocytes (p=0.274; r=0.130) with the severity of pneumonia. However, a weak negative correlation was identified between LMR (p=0.019; r=0.275) and the severity of pneumonia. The conclusion drawn from this study is that LMR has a weak negative correlation with the severity of childhood pneumonia
Item Type: | Thesis (Sarjana) |
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Identification Number: | 0524060136 |
Uncontrolled Keywords: | limfosit, monosit, lymphocyte to monocyte ratio (LMR), derajat keparahan pneumonia |
Divisions: | Fakultas Kedokteran > Pendidikan Dokter |
Depositing User: | Endang Susworini |
Date Deposited: | 27 Feb 2024 06:09 |
Last Modified: | 27 Feb 2024 06:09 |
URI: | http://repository.ub.ac.id/id/eprint/216256 |
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Text (DALAM MASA EMBARGO)
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