Pengaruh Exercise Training terhadap Kadar C-Reactive Protein (CRP) pada Perokok

Mahya, Addini Ainun and Prof. Dr. Titin Andri Wihastuti, S.Kp.,M.Kes. and Ns. Akhiyan Hadi S., S.Kep., M.Biomed (2023) Pengaruh Exercise Training terhadap Kadar C-Reactive Protein (CRP) pada Perokok. Sarjana thesis, Universitas Brawijaya.

Abstract

Merokok dapat meningkatkan insiden Cardiovascular Disease (CVD) dengan cara meningkatkan inflamasi kronis pada pembuluh darah dan menyebabkan aterosklerosis. Proses inflamasi tersebut, dapat mempengaruhi peningkatan kadar C-Reactive Protein (CRP). Selain itu, aktivitas fisik seperti Exercise training juga dapat mempengaruhi kadar (C-Reactive Protein) CRP dalam tubuh. Exercise training dapat menurunkan produksi sitokin proinflamasi sehingga biomarker inflamasi berkurang. Penelitian ini bertujuan untuk mengetahui pengaruh dari melakukan exercise training terhadap kadar C-Reactive Protein (CRP) pada perokok. Metode penelitian ini adalah Quasi Eksperimen dengan Pretest dan Posttest Nonequivalent Control Group Design. Penelitian ini melibatkan 20 partisipan yang terdiri dari 10 partipan pada kelompok intervensi yaitu perokok dan 10 partisipan kelompok kontrol yaitu nonperokok. Sampel yang dipilih menggunakan teknis purposive sampling berdasarkan kriteria inklusi dan eksklusi. Data penelitian didapatkan dari pengisian kuisioner, pemeriksaan sampel darah dan tes Hypersensitive C-Reactive Protein (Hs-CRP) sebelum serta sesudah exercise training untuk menganalisis kadar CRP. Analisis data yang digunakan adalah uji Wilcoxon untuk menganalisis perbedaan kadar CRP sebelum dan sesudah exercise training pada masing – masing kelompok dan uji Mann Whitney untuk membandingkan perbedaan kadar CRP antar kelompok. Didapatkan hasil uji statistik tidak terdapat perbedaan yang signifikan antara kadar CRP sebelum dan sesudah exercise training pada kedua kelompok. Namun, terdapat perbandingan yang signifikan antara kadar CRP pada kelompok kontrol dan intervensi. Dilihat dari rata – rata kadar CRP mengalami penurunan setelah dilakukan exercise training pada kedua kelompok. Sebaiknya kebiasaan exercise training dapat dilanjutkan sebagai perubahan gaya hidup yang baik khususnya pada perokok.

English Abstract

Smoking can increase the incidence of cardiovascular disease (CVD) by increasing chronic inflammation in the blood vessels and causing atherosclerosis. The inflammatory process can affect the increase in C-Reactive Protein (CRP) levels. In addition, physical activity such as exercise training can also affect CRP levels in the body. Exercise training can reduce the production of proinflammatory cytokines so that inflammatory biomarkers are reduced. This study aims to determine the effect of exercise training on C-Reactive Protein (CRP) levels in smokers. This research method was Quasi Experiment with Pretest and Posttest Nonequivalent Control Group Design. This study involved 20 participants consisting of 10 participants in the intervention group, namely smokers and 10 control group participants, namely non-smokers. Samples were selected using purposive sampling technique based on inclusion and exclusion criteria. Research data were obtained from filling out questionnaires, examining blood samples and Hypersensitive C-Reactive Protein (Hs-CRP) tests before and after exercise training to analyze CRP levels. Data analysis used was Wilcoxon test to analyze the difference in CRP levels before and after exercise training in each group and Mann Whitney test to compare the difference in CRP levels between groups. Statistical test results showed no significant difference between CRP levels before and after exercise training in both groups. However, there was a significant comparison between CRP levels in the control and intervention groups. Judging from the average CRP levels decreased after exercise training in both groups. It is recommended that exercise training habits can be continued as a good lifestyle change, especially in smokers.

Item Type:	Thesis (Sarjana)
Identification Number:	0523160078
Uncontrolled Keywords:	C-Reactive Protein (CRP), Exercise Training, Perokok
Divisions:	Fakultas Ilmu Kesehatan > Ilmu Keperawatan, Fakultas Ilmu Kesehatan
Depositing User:	soegeng Moelyono
Date Deposited:	31 Jan 2024 07:52
Last Modified:	31 Jan 2024 07:52
URI:	http://repository.ub.ac.id/id/eprint/213806

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