Kole, Adelin and dr. Suryanti Dwi Pratiwi, Sp.P(K) and dr. Ngakan Putu Parsama Putra, Sp.P(K) and Dr. dr. Nanik Setijowati, M.Kes (2022) Korelasi Kadar Hemoglobin Baseline dengan Kualitas Hidup Pasien Kanker Paru yang Mendapatkan Kemoterapi Berbasis Platinum Berdasarkan Kuisioner EORTC QLQ LC-13. Doktor thesis, Universitas Brawijaya.
Abstract
Latar Belakang: Kanker paru dan terapinya dapat secara signifikan mempengaruhi kualitas hidup pasien, kesejahteraan, dan fungsi sosial sehari-hari. Anemia merupakan kondisi yang sering terjadi pada pasien kanker paru dan dapat mempengaruhi kualitas hidup. Penelitian ini bertujuan untuk menganalisa hubungan antara kadar hemoglobin baseline dan kualitas hidup pasien kanker paru yang menjalani kemoterapi berbasis platinum. Metode: Penelitian cross sectional dilakukan pada 30 pasien KPKBSK penerima kemoterapi berbasis platinum pada Januari 2023 – Februari 2023 di RSUD Saiful Anwar Malang. Data tingkat Hb baseline diperoleh melalui rekam medis sedangkan kualitas hidup pasien dilakukan melalui wawancara menggunakan kuesioner EORTC QLQLC13. Analisis data menggunakan uji korelasi. Dinyatakan bermakna ketika P <0,05. Hasil: nilai koefisien korelasi adalah 0,559 dengan nilai p = 0,001 (p<0,05) untuk korelasi antara Hb baseline dengan indikator pereda nyeri setelah pengobatan dan koefisien korelasi -0,386 dengan nilai p = 0,035 (p<0,05) antara Hb baseline dengan kesulitan menelan. Hasil uji korelasi antara Hb baseline dengan kualitas hidup diperoleh nilai koefisien korelasi -0,096 dengan nilai p 0,615 (p>0,05). Kesimpulan: Berdasarkan indikator kualitas hidup dalam kuesioner ini, ada korelasi yang sifgnifikan antara menurunnya kadar Hb baseline dengan menurunnya pain relief after medication serta meningkatnya disfagia, namun penyebabnya tidak diketahui dan tidak terdapat korelasi yang signifikan antara kadar Hb baseline dengan total skor kualitas hidup.
English Abstract
Background: Lung cancer and its therapy can significantly affect a patient's quality of life, well-being, and daily social functions. Anemia is a condition that often occurs in lung cancer patients and could affect the quality of their life. This study aims to analyze the relationship between baseline haemoglobin levels and quality of life of lung cancer patients undergoing platinum-based chemotherapy. Method: The cross-sectional study was conducted on 30 NSCLC patients who received platinum-based chemotherapy in January 2023 – February 2023 at Dr. Saiful Anwar Hospital Malang. Baseline Hb level data were obtained through medical records while the patient's quality of life assessment was conducted through interviews using the EORTC QLQ-LC13 questionnaire. Data was analyzed using correlation tests. Concluded as significant if p value <0.05. Results: the value of the correlation coefficient was 0.559 with p value = 0.001 (p<0.05) for the correlation between Hb baseline and the indicator of pain relief after medication and the correlation coefficient of -0.386 with p value = 0.035 (p<0.05) between Hb baseline and difficulty swallowing. The results of the correlation test between baseline Hb and quality of life obtained a correlation coefficient value of -0.096 with a p value of 0.615 (p>0.05). Conclusions: Based on the quality of life indicators in this questionnaire, there is a significant correlation between decreased baseline Hb levels and decreased pain relief after medication and increased dysphagia, but the cause is unknown and there is no significant correlation between baseline Hb levels and total quality of life scores.
| Item Type: | Thesis (Doktor) |
|---|---|
| Identification Number: | 062206 |
| Uncontrolled Keywords: | hemoglobin baseline, anemia, kualitas hidup, EORTC QLQ LC 13, kemoterapi berbasis platinum |
| Divisions: | S2/S3 > Doktor Ilmu Kedokteran, Fakultas Kedokteran |
| Depositing User: | Endang Susworini |
| Date Deposited: | 31 Jan 2024 04:01 |
| Last Modified: | 31 Jan 2024 04:01 |
| URI: | http://repository.ub.ac.id/id/eprint/213665 |
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