Utomo, Martin Prayiggo and dr. Isngadi,, M.Kes.,SpAn-TI.,Subsp.An.O.(K) and dr. Ruddi Hartono,, SpAn-TI.,FCTA.,Subsp.An.O.(K) (2023) Analisis Luaran Fetomaternal Dan Kebutuhan Transfusi Pada Pasien Plasenta Akreta Dengan Hemodilusi Preoperatif. Magister thesis, Universitas Brawijaya.
Abstract
Latar Belakang : Morbiditas dan mortalitas yang tinggi pada plasenta akreta terjadi karena risiko perdarahan yang tinggi dan kebutuhan transfusi yang meningkat. Salah satu teknik untuk mengatasi kehilangan darah vaskuler adalah melalui hemodilusi. Tujuan : Mengetahui luaran fetomaternal dan kebutuhan transfusi pada pasien plasenta akreta dengan hemodilusi Metode : Observasional analitik, dengan desain penelitian kohort retrospektif. Kriteria inklusi melibatkan pasien yang telah didiagnosis dengan plasenta akreta, menjalani tindakan sectio caesarea, dan menerima hemodilusi di RSU Dr. Saiful Anwar Malang. Variabel yang diamati mencakup jumlah hemodilusi, kadar hemoglobin sebelum hemodilusi, kadar hemoglobin setelah hemodilusi, kadar hemoglobin setelah operasi, skor APGAR pada menit ke-0 dan menit ke-5, jumlah transfusi, jumlah perdarahan, serta luaran bagi bayi dan ibu. Hasil : Total subjek penelitian sebanyak 120, dengan rata-rata usia 32,8 tahun, jumlah hemodilusi sebesar 1913,56, jumlah perdarahan sebanyak 4136 ml. Kadar hemoglobin rata-rata (sebelum operasi vs. setelah hemodilusi vs. setelah operasi; mg/dl) adalah 10,2 vs. 8,95 vs. 8,95, dan skor APGAR (menit ke-0 vs. menit ke-5) adalah 5 vs. 7. Hasil uji korelasi dengan regresi linier berganda menunjukkan adanya hubungan signifikan (p<0,05). Kesimpulan : Semakin tinggi jumlah hemodilusi yang diberikan pada pasien, semakin rendah jumlah transfusi yang diperlukan, dan sebaliknya.
English Abstract
Background: High morbidity and mortality in placenta accreta occurs due to the high risk of bleeding and increased transfusion requirements. One technique in managing vascular blood loss is through hemodilution. Objective: To investigate the fetomaternal outcomes and transfusion requirements in placenta accreta patients with hemodilution Methods: This study employed an observational analytic approach with a retrospective cohort research design. Inclusion criteria were patients diagnosed with placenta accreta who underwent a caesarean section and received hemodilution at RSU Dr. Saiful Anwar Malang. The variables were observed included the number of hemodilutions, pre-hemodilution hemoglobin levels, hemoglobin levels posthemodilution, hemoglobin levels post-surgery, APGAR scores at the 0th and 5th minutes, volume of transfusions, volume of bleeding, and outcomes for both the infant and the mother. Results: The total number of research subjects was 120, with an average age of 32.8 years. The mean amount of hemodilution administered was 1913.56, and the total bleeding volume was 4136 ml. Mean hemoglobin levels (pre-surgery vs. posthemodilution vs. post-surgery; mg/dl) were 10.2 vs. 8.95 vs. 8.95, while the APGAR scores (0th minute vs. 5th minute) were 5 vs 7. The results of the correlation test using multiple linear regression demonstrated a significant relationship (p<0.05). Conclusion: The administration of a higher amount of hemodilution to patients is significantly associated with a reduced need for transfusions, and vice versa.
| Item Type: | Thesis (Magister) |
|---|---|
| Identification Number: | 042306 |
| Uncontrolled Keywords: | Plasenta Akreta, perdarahan, hemodilusi, transfusi, Placenta Accreta, Bleeding, Hemodilution, Transfusion. |
| Divisions: | Profesi Kedokteran > Spesialis Anestesiologi dan Terapi Intensif, Fakultas Kedokteran |
| Depositing User: | Unnamed user with username ihwan |
| Date Deposited: | 12 Jan 2024 03:38 |
| Last Modified: | 12 Jan 2024 03:38 |
| URI: | http://repository.ub.ac.id/id/eprint/209027 |
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Text (MASIH DALAM MASA EMBARGO)
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