Riskiyana, - and dr. Machlusil Husna, Sp. S (K) and dr. Rodhiyan Rakhmatiar, Sp.S (K), FINA, M. Biomed and Prof. Dr. dr. Sri Andarini, M.Kes (2023) Hubungan Faktor Klinis Demografis dan Antiseizure Medication (ASM) dengan Gangguan Kognitif yang Dinilai Menggunakan Skor CERAD pada Pasien Epilepsi di RSUD Dr. Saiful Anwar Jawa Timur. Magister thesis, Universitas Brawijaya.
Abstract
Latar Belakang : Epilepsi merupakan kelainan otak dengan kecenderungan terus menerus untuk menimbulkan bangkitan epileptik dengan berbagai konsekuensi. Individu dengan epilepsi berisiko juga terjadi berbagai masalah kesehatan seperti gangguan kognitif. Penyebab gangguan kognitif pada epilepsi cenderung multifakorial. Dibutuhkan penelitian untuk mengetahui hubungan faktor-faktor yang mempengaruhi gangguan kognitif pada pasien epilepsi Tujuan Penelitian : Mengetahui hubungan faktor Klinis Demografis dan Antiseizure Medication (ASM) dengan gangguan kognitif yang dinilai menggunakan skor CERAD pada pasien epilepsi di RSUD dr. Saiful Anwar Jawa Timur Metode dan Sampel Penelitian : Penelitian cross-sectional dengan jumlah subyek penelitian sebanyak 25 responden, yang dilakukan di Poli Memori Poli Saraf RSUD Dr. Saiful Anwar Jawa Timur. Hasil Penelitian : Dari penelitian ini didapatkan bahwa tidak terdapat hubungan faktor tipe bangkitan, durasi epilepsi, usia onset epilepsi, frekuensi bangkitan dan Antiseizure Medication (ASM) dengan gangguan kognitif yang dinilai dengan skor CERAD (p= 0.245 ; 0.683; 0.536; 0.162, 0.061 >0.05) Kesimpulan :. Tidak terdapat pengaruh faktor tipe bangkitan, durasi epilepsi, usia onset epilepsi, frekuensi bangkitan dan Antiseizure Medication (ASM) dengan gangguan kognitif yang dinilai dengan skor CERAD
English Abstract
Background: Epilepsy is a brain disorder with a tendency to cause unprovoked seizure with various consequences. Individuals with epilepsy are also at risk of various complications, one of them is cognitive impairment. The causes of cognitive impairment in epilepsy were multifactorial. This study aims to perceive factors that influence the cognitive impairment in epilepsy patients. Objective: To determine the relationship between Demographic Clinical Factors and Antiseizure Medication (ASM) with cognitive impairment assessed using CERAD scores in epilepsy patients at dr. Saiful Anwar General Hospital, East Java. Research Methods and Samples: This study is a cross-sectional study with a total of 25 research subjects, conducted at the Memory Neurological Outpatient Clinics at dr. Saiful Anwar General Hospital, East Java in December 2022 until February 2023. Research Results: This study define there were no influence of factors such as type of seizure, duration of epilepsy, age of onset of epilepsy, frequency of seizure and Antiseizure Medication (ASM) with cognitive impairment in epileptic patients whom assessed by CERAD score (p = 0.245; 0.683; 0.536; 0.162, 0.061 >0.05). Conclusion: There were no significant relationship of factors such as type of seizure, duration of epilepsy, age of onset of epilepsy, frequency of seizure and Antiseizure Medication (ASM) with cognitive impairment assessed by CERAD score.
| Item Type: | Thesis (Magister) |
|---|---|
| Identification Number: | 0423060099 |
| Uncontrolled Keywords: | Epilepsi, tipe bangkitan, durasi epilepsi, usia onset, frekuensi bangkitan , Antiseizure Medication (ASM), gangguan kognitif, CERAD |
| Subjects: | 600 Technology (Applied sciences) > 616 Diseases > 616.8 Diseases of nervous system and mental disorders |
| Divisions: | Profesi Kedokteran > Spesialis Neurologi, Fakultas Kedokteran |
| Depositing User: | Endang Susworini |
| Date Deposited: | 12 Dec 2023 08:21 |
| Last Modified: | 12 Dec 2023 08:21 |
| URI: | http://repository.ub.ac.id/id/eprint/205209 |
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