Andini, Reza and drh. Reza Yesica, (2023) Pengaruh Infeksi Fasciola Sp. Terhadap Aktivitas Alanine Aminotransferase (Alt) Dan Aspartate Aminotransferase (Ast) Sapi Perah Di Dusun Busu, Kecamatan Jabung, Kabupaten Malang. Sarjana thesis, Universitas Brawijaya.
Abstract
Dusun Busu yang terletak di Kecamatan Jabung, Kabupaten Malang, merupakan salah satu sentra peternakan sapi perah di Jawa Timur. Kejadian penyakit Fasciola sp. dapat menyebabkan kerusakan pada hepar sehingga dapat mengganggu proses metabolisme dan menurunkan produktivitas dari sapi perah. Kerusakan hepar dapat ditinjau dari kadar ALT dan AST yang meningkat dalam serum darah. Penelitian bersifat observasional deskriptif yang bertujuan mendeskripsikan kadar ALT dan AST dalam serum darah sapi perah yang terinfeksi cacing Fasciola sp. Pengumpulan sampel menggunakan teknik purposive sampling kemudian perhitungan jumlah sampel minimal menggunakan rumus Slovin. Pemeriksaan sampel feses dilakukan dengan Parfitt and Banks untuk mengetahui sapi yang terinfeksi Fasciola sp. Dua kejadian infeksi Fasciola sp. ditemukan dari pemeriksaan 100 sampel feses. Sampel darah dari sapi yang positif terinfeksi Fasciola sp. diambil dan dilakukan pemeriksaan ALT dan AST. Dua sampel tersebut menunjukkan terjadi penurunan kadar AST dan ALT. Data kadar ALT dan AST yang didapatkan lalu dikaji dengan metode meta analisis. Hasil kajian meta analisis menunjukkan terdapat 16 jurnal yang membahas topik serupa dengan jumlah sampel 20 ekor sapi yang terinfeksi dan 20 ekor sapi sehat. Rata-rata kadar AST dan ALT sapi yang terinfeksi Fasciola sp. dari kajian meta analisis yaitu 113.67 U/L dan 80.01 U/L, sedangkan rata-rata dari sapi yang sehat yaitu 82.45 U/L dan 54.93 U/L. Kemudian dilakukan uji statistik Chi Square dan pembahasan secara deskriptif. Kajian meta analisis menunjukkan bahwa infeksi Fasciola sp. tidak memiliki hubungan terhadap peningkatan kadar ALT dan AST (P > 0.05).
English Abstract
Busu Subdistrict, located in Jabung District, Malang Regency, is one of the centers for dairy farming in East Java. The incidence of Fasciola sp. can cause damage to the liver so that it can interfere with metabolic processes and reduce the productivity of dairy cows. Liver damage can be seen from the increased levels of ALT and AST in the blood serum. This research is a descriptive observational study that aims to describe the levels of ALT and AST in the blood serum of dairy cows infected with Fasciola sp. Collecting samples using purposive sampling technique then calculating the minimum number of samples using the Slovin formula. Examination of faecal samples was carried out by Parfitt and Banks to determine which cows were infected with Fasciola sp. Two cases of Fasciola sp. infection. found from examination of 100 stool samples. Blood samples from cows that were positive for Fasciola sp. had been taken and examined ALT and AST. The two samples showed a decrease in AST and ALT levels.. The obtained data on ALT and AST levels were then examined using the meta-analysis method. The results of the meta-analysis showed that there were 16 journals discussing similar topics with a sample size of 20 infected cows and 20 healthy cows. The average AST and ALT levels of cows infected with Fasciola sp. from the meta-analysis study, namely 113.67 U/L and 80.01 U/L, while the average of healthy cows was 82.45 U/L and 54.93 U/L. Then the Chi Square statistical test was carried out and the discussion was descriptive. The meta-analysis study showed that infection with Fasciola sp. had no relation to the increase in ALT and AST levels (P> 0.05)
Other obstract
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| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | 0523130028 |
| Uncontrolled Keywords: | Alanin Aminotransferase (ALT), Aspartat Aminotransferase (AST), Fasciola sp., Hepar, Sapi Perah, Alanin Aminotransferase (ALT), Aspartat Aminotransferase (AST), Fasciola sp., Hepar, Dairy cow |
| Subjects: | 600 Technology (Applied sciences) > 636 Animal husbandry > 636.08 Specific topics in animal husbandry > 636.089 Veterinary medicine |
| Divisions: | Fakultas Kedokteran Hewan > Kedokteran Hewan |
| Depositing User: | Nur Cholis |
| Date Deposited: | 28 Aug 2023 07:40 |
| Last Modified: | 28 Aug 2023 07:40 |
| URI: | http://repository.ub.ac.id/id/eprint/202672 |
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