Kamilah, Salsabiella Fawziyah and Dr. dr. Ery Olivianto,, Sp.A(K) and dr. Agustin Iskandar, M.Kes,, Sp.PK(K) (2023) Hubungan Anatara Kadar Hemoglobin dan Indeks Eritrosit dengan Status Gizi, Gambaran Radiologis, dan Manifestasi Ekstraparu pada Pasien Tuberkulosis Anak di RSUD Dr. Saiful Anwar Malang. Sarjana thesis, Universitas Brawijaya.
Abstract
Menurut WHO, Indonesia termasuk negara “High Burden Countries” pada kasus TB yang menyumbang dua per tiga kasus TB baru di dunia. Umumnya, orang dewasa yang terinfeksi TB dapat menularkan melalui inhalasi kepada anakanak. Beban kasus TB pada anak-anak tidak bisa diketahui secara pasti karena kurangnya alat diagnostik yang “child friendly” dan tidak adekuatnya sistem pencatatan serta pelaporan kasus TB anak. TB menular melalui sistem pernapasan, tetapi karena sifatnya yang limogenik dan hematogenik sehingga dapat menginfeksi di organ-organ lain. Tujuan penelitian ini adalah untuk mengetahui hubungan antara kadar hemoglobin dan indeks eritrosit terhadap derajat keparahan berupa status gizi, gambaran radiologis, dan manifestasi ekstraparu pada pasien TB anak. Penelitian ini menggunakan metode observasional analitik dan dilakukan menggunakan pendekatan desain cross sectional. Pengambilan sampel menggunakan teknik consecutive sampling dan didapatkan 38 pasien yang telah memenuhi kriteria inklusi pada Juli-Desember 2021. Berdasarkan hasil uji statistik parametrik dan non-parametrik, pada penelitian ini menunjukkan bahwa tidak terdapat hubungan yang signifikan antara kadar Hb dan indeks eritrosit dengan status gizi, gambaran radiologi, dan manifestasi ekstra paru. Sampel didominasi dengan anemia derajat ringan dengan morfologi normokrom normositik pada gizi buruk, gambaran radiologi berat, serta ada maupun tidaknya manifestasi ekstra paru. Sedangkan pada anemia derajat ringan degan morfologi hipokrom mikrositik banyak pada anak dengan status gizi baik dan kurang. Dapat disimpulkan pada penelitian ini kadar Hb dan indeks eritrosit masih belum bisa digunakan sebagai prediktor untuk memprediksi derajat keparahan melalui temuan abnormalitas pada status gizi, gambaran radiologi, dan manifestasi ekstra paru pada anak penderita TB paru.
English Abstract
According to WHO, Indonesia is a "High Burden Country" in terms of TB cases, which accounts for two-thirds of new TB cases in the world. Generally, adults who are infected with TB can transmit it by inhalation to children. The TB caseload in children cannot be known with certainty because of the lack of "child friendly" diagnostic tools and the inadequate system for recording and reporting TB cases in children. TB is transmitted through the respiratory system, but because of its lymphogenic and hematogenic nature, it can infect other organs. The purpose of this study was to determine the relationship between hemoglobin and RBC indices levels on the degree of severity in the form of nutritional status, radiological features, and extrapulmonary manifestations in pediatric TB patients. This study used an analytic observational method and was carried out using a cross sectional design approach. Sampling used the consecutive sampling technique and obtained 38 patients who met the inclusion criteria in July-December 2021. Based on the results of parametric and non-parametric statistical tests, this study showed that there was no significant relationship between Hb and RBC indices levels and nutritional status , radiological features, and extrapulmonary manifestations. Samples were dominated by mild anemia with normocytic normochromic morphology in malnutrition, severe radiological features, and the presence or absence of extrapulmonary manifestations. Whereas in mild anemia with microcytic hypochromic morphology, there are many children with good and poor nutritional status. It can be concluded that in this study Hb levels and erythrocyte index could not be used as predictors to predict the degree of severity through findings of abnormalities in nutritional status, radiological features, and extrapulmonary manifestations in children with pulmonary TB.
Other obstract
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| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | 0522060357 |
| Uncontrolled Keywords: | Hb, MCV, MCH, tuberkulosis anak, status gizi, gambaran radiologi, manifestasi ekstra paru |
| Subjects: | 600 Technology (Applied sciences) > 610 Medicine and health |
| Divisions: | Fakultas Kedokteran > Pendidikan Dokter |
| Depositing User: | Endang Susworini |
| Date Deposited: | 09 May 2023 06:37 |
| Last Modified: | 09 May 2023 06:37 |
| URI: | http://repository.ub.ac.id/id/eprint/199107 |
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Text (DALAM MASA EMBARGO)
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