Kurniawan, Ferdi and Dr. dr. Rosy Aldina, Sp.M(K) and dr. Holipah, PhD (2023) Analisis Objektif Pengaruh Komponen Pemeriksaan Dry Eye Disease Terhadap Derajat Keparahan Dry Eye Disease Pada Populasi di Kabupaten Malang. Magister thesis, Universitas Brawijaya.
Abstract
Tujuan: Menganalisis derajat keparahan komponen pemeriksaan dry eye disease (DED) yang paling berperan pada derajat keparahan DED, serta menganalisis faktor resiko yang berhubungan dengan kejadian DED. Metode: Desain penelitian ini adalah studi cross sectional berbasis populasi pada tiga desa di Kabupaten Malang. Rentang usia responden antara 40 hingga 84 tahun. Dilakukan anamnesis terkait status demografi dan identifikasi faktor resiko, serta pemeriksaan klinis DED yang meliputi kuesioner OSDI, tear breakup time (TBUT), derajat meibomian gland dysfunction (MGD), dan tes Schirmer I. Hubungan variabel yang menjadi faktor resiko terhadap kejadian DED dianalisis dengan uji korelasi. Pengaruh komponen pemeriksaan DED terhadap derajat keparahan DED diuji menggunakan uji regresi ordinal. Hasil: Prevalensi DED pada populasi penelitian ini sebesar 42,5%. Pterygium konsisten memiliki pengaruh kuat dengan kejadian DED pada analisis multivariat (OR:1,44) dan bivariat (OR:1,53), sedangkan penambahan usia hanya pada analisis bivariat (OR:1,01). Pada analisis multivariat, tidak ditemukan pengaruh signifikan dari seluruh komponen pemeriksaan DED terhadap derajat keparahan DED, hasil sebaliknya ditemukan pada analisis bivariat. Kesimpulan: Faktor resiko yang berhubungan erat dengan kejadian DED adalah pterygium dan penambahan usia. Tidak terdapat perbedaan antara derajat keparahan komponen pemeriksaan DED terhadap derajat keparahan DED bila dianalisis secara bersamaan, kecuali pada analisis masing-masing komponen pemeriksaan secara terpisah
English Abstract
Objective: To analyze the association between dry eye disease (DED) clinical examination and DED severity grade, as well as analyze the risk factors associated with the incidence of DED. Method: This is a population-based cross-sectional study. The age of respondents ranged between 40 to 84 years old. Basic demographic data were recorded parallel with the risk factors identified. All participants underwent clinical examination of DED which included an OSDI questionnaire, tear breakup time (TBUT), degree of meibomian gland dysfunction (MGD), and Schirmer I test. Data were analyzed using correlation and ordinal regression tests. Results: The prevalence of DED in the study population was 42.5%. Pterygium consistently has a strong relationship with the incidence of DED both in multivariate (OR:1.44) and bivariate analysis (OR:1.53), while aging is only significant in bivariate analysis (OR:1.01). In multivariate analysis, no significant effect was observed between all components of DED clinical examination to the severity of DED, the opposite result was found in bivariate analysis. Conclusion: The risk factors of DED that are closely related in statistical analysis were pterygium and aging. There is no difference between the degree of severity of DED clinical examination to the severity of DED when analyzed simultaneously, except in the analysis of each examination separately
Other obstract
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| Item Type: | Thesis (Magister) |
|---|---|
| Identification Number: | 0422060149 |
| Uncontrolled Keywords: | Severitas Dry Eye Disease, Pemeriksaan Klinis Dry Eye Disease, Faktor Resiko Dry Eye Disease,-Severity Of Dry Eye Disease, Clinical Examination Of Dry Eye Disease, Risk Factors For Dry Eye Disease |
| Subjects: | 600 Technology (Applied sciences) > 617 Surgery, regional medicine, dentistry, ophthalmology, otology, audiology > 617.7 Ophthalmology |
| Divisions: | Profesi Kedokteran > Spesialis Ilmu Kesehatan Mata, Fakultas Kedokteran |
| Depositing User: | Endang Susworini |
| Date Deposited: | 05 May 2023 04:03 |
| Last Modified: | 05 May 2023 04:03 |
| URI: | http://repository.ub.ac.id/id/eprint/198731 |
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Text (DALAM MASA EMBARGO)
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