Shafira, Dhea Amalia and drg. Yuliana Ratna Kumala,, Sp.KG (2021) Efektivitas Minyak Atsiri Rimpang Kencur (Kaempferia galanga L.) Sebagai Bahan Medikamen Saluran Akar Terhadap Streptococcus sanguinis Secara In Vitro. Sarjana thesis, Universitas Brawijaya.
Abstract
Perawatan Saluran Akar (PSA) merupakan perawatan endodontik untuk mengeliminasi infeksi bakteri dan inflamasi yang disebabkan oleh jaringan pulpa. Bakteri gram positif bersifat anaerob fakultatif yang mendominasi pada kasus kegagalan perawatan saluran akar ialah Streptococcus sanguinis. Mengeliminasi seluruh bakteri pada saluran akar dapat dengan pemberian bahan medikamen. Kencur (Kaempferia galanga L.) merupakan salah satu obat tradisional yang mempunyai banyak manfaat. Minyak atsiri rimpang kencur memiliki aktivitas sebagai antibakteri. Tujuan dari penelitian ini ialah untuk mengetahui efektivitas minyak atsiri rimpang kencur (Kaempferia galanga L.) sebagai bahan medikamen saluran akar terhadap Streptococcus sanguinis secara in vitro. Metode yang digunakan ialah dilusi tabung untuk mengetahui Kadar Hambat Minimum (KHM) dan Kadar Bunuh Minimum (KBM) minyak atsiri rimpang kencur konsentrasi 4%, 5%, 6%, 7%, 8%, 9% terhadap pertumbuhan bakteri Streptococcus sanguinis. Hasil uji statistika ANOVA sig=0.000 (p<0.05) menunjukkan terdapat perbedaan yang signifikan dari rata-rata setiap konsentrasi minyak atsiri rimpang kencur terhadap jumlah koloni bakteri Streptococcus sanguinis. Hasil uji Korelasi Pearson terdapat hubungan yang signifikan antara peningkatan konsentrasi minyak atsiri rimpang kencur dengan pertumbuhan bakteri Streptococcus sanguinis dengan koefisien r hitung sebesar -0.899. KHM pada penelitian ini ialah konsentrasi 6%, dan KBM pada penelitian ini ialah konsentrasi 7%. Kesimpulan pada penelitian ini ialah minyak atsiri rimpang kencur (Kaempferia galanga L.) efektif sebagai bahan medikamen saluran akar terhadap Streptococcus sanguinis secara in vitro.
English Abstract
Root Canal Treatment (RCT) is an endodontic treatment to eliminate bacterial infection and inflammation caused by the pulp tissue. Gram positive bacteria that has anaerobic facultative character is dominant in failure root canal treatment is Streptococcus sanguinis. To eliminate all bacteria in the root canal can use medicament materials. Kencur (Kaempferia galanga L.) is a traditional medicine that has many benefits. Kaempferia galanga L. rhizome essential oil has an antibacterial activity. The purpose of this research to determine the effectiveness of Kaempferia galanga L. rhizome essential oil as a root canal medicament against Streptococcus sanguinis by in vitro study. The method that used in this research is dilution, to see the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of Kaempferia galanga L. rhizome essential oil with a concentration of 4%, 5%, 6%, 7%, 8%, 9% against Streptococcus sanguinis bacteria. The results of the ANOVA statistical test sig=0.000 (p <0.05) showed that there was a significant difference between the average concentration of each Kaempferia galanga L. essential oil concentration to the amount of Streptococcus sanguinis bacterial colonies. The results of the Pearson Correlation test showed that has significant relationship between the concentration increased of the Kaempferia galanga L. essential oil and the growth of Streptococcus sanguinis with a coefficient -0.899. The MIC of this research's concentration was 6%, and the MBC of this research's concentration was 7%. The conclusion of this research that Kaempferia galanga L. rhizome essential oil is effective as a root canal medicament against Streptococcus sanguinis by in vitro study.
| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | 0521140009 |
| Uncontrolled Keywords: | Perawatan Saluran Akar (PSA), Streptococcus sanguinis, Minyak atsiri rimpang kencur (Kaempferia galanga L.),Root Canal Treatment (RCT), Streptococcus sanguinis, Kaempferia galanga L. rhizome essential oil. |
| Subjects: | 600 Technology (Applied sciences) > 617 Surgery, regional medicine, dentistry, ophthalmology, otology, audiology > 617.6 Dentistry |
| Divisions: | Fakultas Kedokteran Gigi > Kedokteran Gigi |
| Depositing User: | soegeng sugeng |
| Date Deposited: | 17 Jun 2022 01:16 |
| Last Modified: | 17 Jun 2022 01:16 |
| URI: | http://repository.ub.ac.id/id/eprint/190998 |
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