Sugiarto, Fadhil Akbar and Prof. Dr. Warsito,, MS and Drs. Suratmo,, M.Sc (2021) Studi Reaksi Nitrasi Sinamaldehid Hasil Isolasi dari Minyak Kayu Manis (Cinnamomum cassia). Sarjana thesis, Universitas Brawijaya.
Abstract
Penelitian ini bertujuan mempelajari reaksi spesifik gugus aldehid untuk keperluan mengisolasi sinamaldehid dan reaksi spesifik cincin aromatis untuk membuat senyawa turunan o-Nitrosinamaldehid. Dalam penelitian ini isolasi sinamaldehid dilakukan dengan metode penggaraman menggunakan NaHSO3 jenuh disertai pencucian garam dengan etanol 98% dan hidrolisis dengan HCl 5%. Sintesis o-Nitrosinamaldehid dilakukan dengan mereaksikan sinamaldehid dalam asetat anhidrid dengan campuran asam nitrat (65% )-asam asetat glasial yang ditambahkan tetes demi tetes pada suhu dibawah 10o C. Waktu pengeraman reaksi divariasi selama 2, 4, 6, dan 8 hari dihitung sejak pengadukan dihentikan dan perbandingan mol sinamaldehid : asam nitrat divariasi 1:1, 1:2, dan 1:3. Karakterisasi produk isolasi dan sintesis menggunakan KLT, FTIR, dan GC-MS. Berdasarkan hasil hasil karakterisasi dengan GC-MS diketahui bahwa sinamaldehid hasil isolasi dan o-Nitrosinamaldehid hasil sintesis memiliki kemurnian 100%. Hasil KLT plat silika (eluen n-heksana:etanol dengan perbandingan volume 0,7:12,7) produk sintesis Rf 0,47 dan karakterisasi dengan FTIR menunjukkan adanya ikatan N-O (ortho), C=O untuk aldehid. Perbandingan mol sinamaldehid : mol asam nitrat paling optimum adalah 1:2 dan waktu reaksi optimum selama pengeraman reaksi 4 hari dengan persen yield 49,94%.
English Abstract
This study aims to study the specific reactions of aldehyde groups to isolate cinnamaldehyde and aromatic ring-specific reactions to create o-Nitrocinnamaldehyde derivative compounds. In this study, cinnamaldehyde isolation was carried out by salting method using saturated NaHSO3 followed by salt-leaching using ethanol 98% and hydrolyzed by HCl 5%. The synthesis of o-Nitrocinnamaldehyde is performed by reacting cinnamaldehyde in anhydrous acetic acid with a mixture of nitric acid (65% )-acetic acid added drop by drop at temperatures below 10 oC. Reaction times varied over 2, 4, 6, and 8 days calculated since stirring was discontinued and the ratio of mole cinnamaldehyde:nitric acid varied by 1:1, 1:2, and 1:3. Characterization of isolation and synthesis products using TLC, FTIR, and GC-MS. Based on the results of characterization with GC-MS it is known that cinnamaldehyde is the result of isolation and o-Nitrocinnamaldehyde synthesis results have a purity of 100%. The results of the silica plate TLC (eluent n-hexane:ethanol with a volume ratio of 0.7:12,7) of the synthesis product Rf 0.47 and characterization with FTIR indicate the presence of N-O (ortho), C=O bonds for aldehydes. The most optimum Comparison of mol cinnamaldehyde: nitric acid mole is 1:2 and the optimum reaction time during the 4-day reaction flush with a yield of 49.94%.
| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | 0521090031 |
| Uncontrolled Keywords: | Cinnamaldehyde, o-Nitrocinnamaldehyde, NaHSO3 reagent, HNO3 reagent. |
| Subjects: | 500 Natural sciences and mathematics > 540 Chemistry and allied sciences |
| Divisions: | Fakultas Matematika dan Ilmu Pengetahuan Alam > Kimia |
| Depositing User: | agung |
| Date Deposited: | 13 May 2022 03:30 |
| Last Modified: | 18 May 2022 03:45 |
| URI: | http://repository.ub.ac.id/id/eprint/190424 |
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Text (DALAM MASA EMBARGO)
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