Canora, Salma Desra and drh. Dian Vidiastuti, M.Si. (2021) Perbandingan Efek Anestetik Ketamine–Xylazine dan Ketamine– Medetomidine pada Biawak (Varanus salvator). Sarjana thesis, Universitas Brawijaya.
Abstract
Pemilihan obat anestesi pada biawak harus dipertimbangkan dengan baik guna menghasilkan efek yang aman dan maksimal. Obat anestesi yang sering digunakan pada reptil adalah ketamine yang merupakan obat anestesi disosiatif. Ketamine dapat dikombinasikan dengan xylazine atau medetomidine guna meningkatkan efektivitas kerja ketamine. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh pemberian anestetik ketamine–xylazine dan ketamine–medetomidine berdasarkan onset, durasi anestesi, laju denyut jantung, dan laju respirasi pada biawak. Delapan belas ekor biawak berumur 1 tahun dengan panjang tubuh 40 – 50 cm dibagi menjadi 2 kelompok perlakuan. Perlakuan pertama diinjeksi ketamine–xylazine 40 mg/Kg BB dan 1 mg/Kg BB secara intramuskular. Perlakuan kedua diinjeksi ketamine–medetomidine 10 mg/Kg BB dan 0.1 mg/kg BB secara intramuskular. Onset, durasi anestesi, laju denyut jantung, dan laju respirasi diukur sebelum injeksi sampai hewan sadar dengan jangka waktu 10 menit. Data penelitian dianalisa menggunakan uji T tidak berpasangan dengan tingkat kepercayaan 95%. Hasil penelitian pemberian ketamine–xylazine dan ketamine–medetomidine pada biawak menunjukkan bahwa terdapat perbedaan nyata (P<0.05) terhadap onset, laju denyut jantung, dan laju respirasi, namun tidak terdapat perbedaan nyata (P>0,05) terhadap durasi anestesi. Ketamine–xylazine mengasilkan onset (5.5 menit), durasi anestesi (145 menit), laju denyut jantung (57.7 bpm), dan laju respirasi (9.4 kali/menit). Ketamine–medetomidine menghasilkan onset (3.6 menit), durasi anestesi (150 menit), laju denyut jantung (51.9 bpm), dan laju respirasi (15.5 kali/menit). Simpulan dari penelitian ini adalah pemberian anestetik ketamine–medetomidine pada biawak menghasilkan onset yang lebih cepat dan durasi yang lebih lama, serta menyebabkan penurunan laju denyut jantung dan peningkatan laju respirasi dibandingkan pemberian ketamine – xylazine.
English Abstract
The selection of anesthetic drugs in monitor lizards must be considered carefully to produce a safe and maximum effect. Ketamine is often used in reptiles that can be combined with xylazine or medetomidine in order to improve the workability of ketamine. This study aimed to determine the effect of ketamine-xylazine and ketamine-medetomidine based on the onset, duration of anesthesia, heart rate, and respiration rate in monitor lizards. Eighteen 1-year-old monitor lizards with a body length of 40 – 50 cm were divided into 2 treatment groups. The first treatment was injected with ketamine-xylazine 40 mg/Kg BW and 1 mg/Kg BW intramuscularly. The second treatment was injected with ketamine-medetomidine 10 mg/Kg BW and 0.1 mg/kg BW intramuscularly. The onset, duration of anesthesia, heart rate, and respiration rate were measured before injection until the animal regained consciousness every 10 minutes. The research data were analyzed using an independent T-test with a confidence level of 95%. The results showed that giving ketamine–xylazine and ketamine–medetomidine to monitor lizards had a significantly different (P <0.05) on the onset, heart rate, and respiration rate, but not significantly different (P> 0.05) on the duration of anesthesia. Ketamine-xylazine produced onset (5.5 minutes), duration of anesthesia (145 minutes), heart rate (57.7 bpm), and respiration rate (9.4 beats/minute). Ketamine–medetomidine produced onset (3.6 minutes), duration of anesthesia (150 minutes), heart rate (51.9 bpm), and respiration rate (15.5 beats/minute). This study concludes that giving the anesthetic ketamine–medetomidine in monitor lizards results in a faster onset, longer duration, decrease in heart rate, and increase in respiration rate compared with ketamine–xylazine.
Other obstract
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| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | 0521130062 |
| Uncontrolled Keywords: | Kata kunci: biawak, ketamine, xylazine, medetomidine |
| Subjects: | 600 Technology (Applied sciences) > 636 Animal husbandry > 636.08 Specific topics in animal husbandry > 636.089 Veterinary medicine |
| Divisions: | Profesi Kedokteran > Spesialis Dokter Hewan, Fakultas Kedokteran Hewan |
| Depositing User: | yulia Chasanah |
| Date Deposited: | 27 Jan 2022 08:02 |
| Last Modified: | 23 Feb 2022 02:07 |
| URI: | http://repository.ub.ac.id/id/eprint/189012 |
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