"PENGARUH PEMBERIAN EKSTRAK BAWANG HITAM (BLACK GARLIC) TERHADAP KADAR TUMOR NECROSIS FACTOR-α (TNF-α) DAN DERAJAT KEASAMAN (pH) CAIRAN VAGINA PADA TIKUS BUNTING (Rattus norvegicus) MODEL AEROBIC VAGINITIS"

Alivia Hildayanti, Rezha (2021) "PENGARUH PEMBERIAN EKSTRAK BAWANG HITAM (BLACK GARLIC) TERHADAP KADAR TUMOR NECROSIS FACTOR-α (TNF-α) DAN DERAJAT KEASAMAN (pH) CAIRAN VAGINA PADA TIKUS BUNTING (Rattus norvegicus) MODEL AEROBIC VAGINITIS". Magister thesis, Universitas Brawijaya.

Abstract

Aerobic Vaginitis is an infection that occurs in the vagina, caused by aerobic bacteria such as S. Aureus. The prevalence of Aerobic Vaginitis in women is 7-12%. Research on Aerobic Vaginitis in humans and experimental animals is still quite limited. Aerobic Vaginitis is claimed to be treated with antibiotics as well as probiotics, there have been no reports of its association with herbal therapies such as black garlic. Black garlic is known to have antibacterial and anti-inflammatory compounds such as flavonoids, tannins, and terpenoids. This study aims to make Aerobic Vaginitis experimental animals using mice in vivo and also to test the content of chemical compounds in black garlic to then be used as the basis for further research that leads to testing black garlic therapy on Aerobic Vaginitis rats. Making experimental animals using mice to be inoculated with S. Aureus bacteria 2x109 CFU/ml with various doses to find out which dose is right to infect mice so that the Aerobic Vaginitis rat model is successfully made. Aureus and Gram stain was performed to see leukocytes and parabasal cells. The phytochemical test of black garlic will be carried out by extraction using methanol as a solvent to be able to attract the chemical compounds contained in it.

Item Type: Thesis (Magister)
Identification Number: 042106
Subjects: 600 Technology (Applied sciences) > 618 Gynecology, obstetrics, pediatrics, geriatrics > 618.2 Obstetrics
Divisions: S2/S3 > Magister Kebidanan, Fakultas Kedokteran
Depositing User: Unnamed user with username santoso
Date Deposited: 23 Oct 2021 07:46
Last Modified: 24 Feb 2022 04:14
URI: http://repository.ub.ac.id/id/eprint/185463
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