Soegiarto, Ellen (2019) Pengaruh Pemberian Air Rebusan Jamur Kuping Hitam (Auricularia Polytricha) Terhadap Kadar High Density Lipoprotein (Hdl) Dan Low Density Lipoprotein (Ldl) Pada Tikus (Rattus Norvegicus) Model Hiperkolesterolemia. Sarjana thesis, Universitas Brawijaya.
Abstract
Hiperkolesterolemia merupakan peningkatan kadar kolesterol total yang disertai dengan meningkatnya kadar kolesterol Low Density Lipoprotein (LDL) dan menurunnya kadar kolesterol High Density Lipoprotein (HDL). Jamur kuping hitam adalah salah satu spesies jamur yang memiliki banyak manfaat dan nilai nutrisi yang cukup tinggi. Zat yang terkandung dalam jamur kuping hitam dapat menurunkan kadar kolesterol seperti niasin dan polisakarida. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian air rebusan jamur kuping hitam (Auricularia polytricha) dalam menurunkan kadar LDL dan meningkatkan kadar HDL pada tikus (Rattus norvegicus). Penelitian ini bersifat eksperimental dengan menggunakan Rancangan Acak Lengkap (RAL). Hewan model menggunakan tikus putih (Rattus norvegicus) strain Wistar jantan dengan umur 8 – 10 minggu dan berat badan 150 – 200 gram yang dibagi dalam lima kelompok perlakuan, yaitu kelompok negatif, kelompok hiperkolesterol, dan kelompok yang diberi perlakuan air rebusan jamur kuping hitam dosis 1, 2, dan 3 mL/ 200 gram BB. Variabel yang diamati adalah kadar HDL dan LDL yang dianalisis dengan ANOVA. Hasil penelitian menunjukkan tidak ada perbedaan secara signifikan antar kelompok perlakuan (P>0,05). Belum terdapat volume pemberian efektif yang mampu meningkatnkan kadar HDL dan menurunkan kadar LDL sebesar. Kesimpulan penelitian ini adalah pemberian terapi air rebusan jamur kuping hitam mampu meningkatkan kadar HDL dan menurunkan kadar LDL dalam darah.
English Abstract
Hypercholesterolemia is an increase in total cholesterol levels which also increases Low Density Lipoprotein (LDL) cholesterol levels and decreases High Density Lipoprotein (HDL) cholesterol levels. Cloud ear fungus is a species of fungus that has many benefits and high nutritional value. Some substances contained in cloud ear fungus can decrease the cholesterol levels such as niacin and polysaccharides. The purpose of this research is to determine the effect of giving decoction of cloud ear fungus (Auricularia polytricha) in decreasing LDL cholesterol levels and increasing HDL cholesterol levels in hypercholesterolemic rats (Rattus norvegicus). This research is experimental using a completely randomized design (CRD). The animal subject used in the research was male Wistar rats (Rattus norvegicus) at 8-10 weeks of age and 150-200 gram body weight divided into five groups, including negative group, hypercholesterol group, and groups given the decoction of cloud ear fungus with different dose 1, 2, and 3 mL/ 200 gram of body weight. The variables analyzed were levels of HDL, levels of LDL, which would be analyzed with ANOVA. The results showed no significant difference between treatment groups (P>0,05). There weren’t any effective volume of cloud ear fungus decoction administration in this research. The conclusion of this study is the effect of cloud ear fungus decoction administration can increase HDL levels and reduce LDL levels in blood
Other obstract
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| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | SKR/FKH/2019/52/051908990 |
| Uncontrolled Keywords: | Hiperkolesterolemia, Jamur Kuping Hitam, LDL, HDL, Rattus norvegicus, Hypercholesterolemia, Cloud Ear Fungus, LDL, HDL, Rattus norvegicus |
| Subjects: | 600 Technology (Applied sciences) > 636 Animal husbandry > 636.08 Specific topics in animal husbandry > 636.089 Veterinary medicine > 636.089 5 Veterinary medicine (Pharmacology and therapeutics) > 636.089 532 9 Antibiotics in veterinary medicine |
| Divisions: | Fakultas Kedokteran Hewan > Kedokteran Hewan |
| Depositing User: | Nur Cholis |
| Date Deposited: | 19 Jul 2020 05:49 |
| Last Modified: | 21 Oct 2021 03:13 |
| URI: | http://repository.ub.ac.id/id/eprint/176734 |
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