Suaibah (2015) Pengaruh Emisi Partikel Ultrafine Asap Pembakaran Biomassa Terhadap Gambaran Mikroskopis Organ Ginjal Mencit (Mus Musculus). Sarjana thesis, Universitas Brawijaya.
Abstract
Partikel ultrafine merupakan partikel yang berukuran <0,1 µm. Partikel ultrafine dapat dihasilkan dari emisi asap pembakaran biomassa. Partikel ultrafine dapat masuk kedalam alveolus paru-paru melalui sistem pernafasan, sehingga dapat terbawa kedalam sistem peredaran darah dalam tubuh dan ditransfer ke ginjal. Partikel ultrafine dapat menyebabkan kerusakan sel-sel organ ginjal, untuk mengetahui kerusakan organ ginjal akibat partikel ultrafine maka dilakukan penelitian tentang pengaruh emisi partikel ultrafine asap pembakaran biomassa terhadap gambaran mikroskopis organ ginjal mencit (Mus musculus). Penelitian dilakukan dengan memasukkan asap hasil pembakaran biomassa dari Burning Chamber kedalam Exposure Chamber. Di dalam Exposure Chamber terdapat 5 hewan uji mencit. Dalam penelitian ini mencit akan dipapari asap pembakaran biomassa selama selama 90s, 180s, 270s, 360s dan 450s dalam 10 hari, kemudian dibuat preparasi organ ginjal mencit dan diamati kerusakannya dengan perbesaran 400×. Setelah itu asap pembakaran biomassa dimasukkan kedalam Exposure Chamber untuk diukur kosentrasi partikel ultrafinenya. Pengukuran kosentrasi partikel ultrafine menggunakan P-Trak UPC model 8525. Hasil dari penelitian ini menunjukkan adanya korelasi yang siknifikan antara jumlah partikel ultrafine yang terkandung asap pembakaran biomassa terhadap kerusakan organ ginjal mencit. Semakin besar partikel ultrafine yang terkandung dalam asap pembakaran biomassa, semakin besar pula persentase kerusakan organ ginjal pada mencit
English Abstract
Ultrafine particles that are particles with the diameter of <0.1 µm have been identified to affect on human health. Ultrafine particles can penetrate the lung alveoli through respiratory system to the kidney causing to damage to the cells. This research was aimed to study the influences of ultrafine particles emitted by biomass burning to the mice kidney (Mus musculus). This study was conducted by inserting of biomaas burning smokes into a chamber there has been five mice were put inside in advance. The mice was exposed by the smoke for a varied time of 0s, 90s, 180s, 270s, 360s and 450s in one day. The treatment was repeated for 10 days. After 10 days, the mice kidney was observed using a microscope with magnification of 400x to see the damage. The concentration of ultrafne particles in the chamber was measured using a TSI 8525 P Trak particle counter. The results showed that there were significant linearly correlation between a number of ultrafine particles in biomass burning smokes and the kidney damage.
| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | SKR/MIPA/2015/149/051504004 |
| Subjects: | 500 Natural sciences and mathematics > 530 Physics |
| Divisions: | Fakultas Matematika dan Ilmu Pengetahuan Alam > Fisika |
| Depositing User: | Budi Wahyono Wahyono |
| Date Deposited: | 30 Jun 2015 10:14 |
| Last Modified: | 30 Jun 2015 10:14 |
| URI: | http://repository.ub.ac.id/id/eprint/154172 |
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