Pratiwi, IntanHayyu (2015) Efek Pemberian Jus Tomat (Solanum Lycopersicum) Dalam Mencegah Peningkatan Kadar Glukosa Darah Pada Tikus Putih (Rattus Novergicus) Strain Wistar Bunting. Sarjana thesis, Universitas Brawijaya.
Abstract
Selama kehamilan, terjadi perubahan metabolisme glukosa seiring dengan meningkatnya kebutuhan simpanan energi untuk persiapan persalinan dan laktasi serta untuk tumbuh-kembangnya janin. Pengaturan makanan dengan nilai indeks glikemik rendah yang tepat diperlukan untuk menjaga kadar glukosa darah tetap terkontrol selama kehamilan sehingga bisa mencegah terjadinya diabetes gestasional. Jus tomat memiliki nilai indeks glikemik rendah dan mengandung antioksidan kuat yaitu likopen. Likopen dapat meningkatkan konsentrasi insulin sehingga menyebabkan menurunnya kadar glukosa darah. Tujuan penelitian ini untuk membuktikan bahwa pemberian jus tomat (Solanum lycopersicum) dapat mencegah peningkatan kadar glukosa darah pada tikus putih (Rattus novergicus) strain wistar bunting. Penelitian ini menggunakan desain eksperimental laboratoris in vivo dengan rancangan penelitian menggunakan Pre and Post test with Control Group Design. Sampel yang digunakan tikus putih (Rattus novergicus) strain wistar betina usia 2-3 bulan yang bunting. Tikus dibagi dalam 4 kelompok yaitu kelompok kontrol (P0) yang diberi pakan dan tidak diberi jus tomat, perlakuan 1 (P1) yang diberi pakan dan jus tomat dengan berat tomat 1,92 gr/ 200gr BB/hari, perlakuan 2 (P2) yang diberi pakan dan jus tomat dengan berat tomat 3,85 gr/ 200gr BB/hari dan perlakuan 3 (P3) yang diberi pakan dan jus tomat dengan berat tomat 7,71 gr/ 200gr BB/hari. Hasil One Way ANOVA menunjukkan terdapat perbedaan yang signifikan kadar glukosa darah pada kelompok (post-test) tikus bunting yang diberi perlakuan jus tomat selama 18 hari dengan dosis yang berbeda-beda dengan nilai p= 0,000 (p< 0,05). Pemberian jus tomat (Solanum lycopersicum) secara oral selama 18 hari mampu mencegah peningkatan kadar glukosa darah pada tikus putih (Rattus novergicus) strain wistar bunting.
English Abstract
During pregnancy, changes in glucose metabolism along with the increasing need for energy savings in preparation for childbirth and lactation as well as for the growth and development of the fetus. Diet with a low glycemic index value necessary for maintaining blood glucose levels under control during pregnancy ,so it can prevent gestational diabetes. Tomato juice has a low glycemic index value and contains a high antioxidant which is called lycopene. Lycopene can increase the concentration of insulin for decreasing of blood glucose levels. The aim of this study is provent by given tomato juice (Solanum lycopersicum) can prevent the increase in blood glucose levels in strain wistar rats (Rattus novergicus) pregnancy. This method of study is an experimental in vivo with Pre and Post Test by Control Group Design. The sample used female white strain wistar rats (Rattus novergicus) aged 2-3 months which is pregnant. Rats were divided into 4 groups: control group (P0) were fed and was not given tomato juice, treatment 1 (P1) were fed and tomato juice of tomato’s weight around 1,92 gr/200gr body weight/day, treatment 2 (P2) were fed and tomato juice of of tomato’s weight around 3,85 gr/200gr body weight/day and treatment 3 (P3) were fed and tomato juice of tomato’s weight around 7,71 gr/200gr body weight/day. The result of One Way ANOVA statistic showed that there are significant differenciate the blood glucose level in the group (post-test) of pregnant rats treated tomato juice for 18 days with a dose different with p = 0,000 (p <0,05). Giving juice tomato (Solanum lycopersicum) orally for 18 days capable of preventing an increase in blood glucose levels in white strain wistar rats (Rattus novergicus) pregnancy.
| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | SKR/FK/2015/765/ 051600820 |
| Subjects: | 600 Technology (Applied sciences) > 618 Gynecology, obstetrics, pediatrics, geriatrics > 618.2 Obstetrics |
| Divisions: | Fakultas Kedokteran > Kebidanan |
| Depositing User: | Kustati |
| Date Deposited: | 10 Feb 2016 15:24 |
| Last Modified: | 10 Feb 2016 15:24 |
| URI: | http://repository.ub.ac.id/id/eprint/125571 |
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