Amila, Ruri Habibatul (2015) Efek Ekstrak Etanol Daun Ketapang (Terminalia Catappa) Sebagai Antibakteri Terhadap Staphylococcus Aureus Isolat 100-Sv Secara In Vitro. Sarjana thesis, Universitas Brawijaya.
Abstract
Staphylococcus aureus merupakan bakteri Gram positif yang sering menjadi penyebab infeksi luka episiotomi dan infeksi luka operasi caesar pada ibu nifas. Terapi antibakteri yang tersedia saat ini memiliki resistensi yang cukup tinggi terhadap bakteri Staphylococcus aureus. Daun ketapang (Terminalia catappa) memiliki kandungan senyawa aktif alkaloid, saponin, flavonoid, tanin, dan kuinon yang diduga mempunyai aktivitas antibakteri terhadap Staphylococcus aureus. Tujuan penelitian ini adalah mengetahui efek ekstrak etanol daun ketapang sebagai antibakteri terhadap Staphylococcus aureus secara in vitro. Penelitian ini adalah penelitian eksperimental laboratoris menggunakan metode difusi lubang/sumuran untuk mengetahui zona hambat ekstrak. Sampel bakteri Staphylococcus aureus diperoleh dari swab vagina. Konsentrasi ekstrak etanol daun ketapang yang digunakan adalah 60%, 50%, 40%, 30%, dan 20% sehingga menghasilkan zona hambat masing-masing yaitu 20,67 mm, 19,29 mm, 18,23 mm, 16,79 mm, dan 15,26 mm. Hasil uji One Way ANOVA menunjukkan terdapat perbedaan pertumbuhan bakteri Staphylococcus aureus yang signifikan setelah pemberian ekstrak etanol daun ketapang (p = 0,000). Uji korelasi Pearson menunjukkan bahwa terdapat hubungan bermakna antara pemberian ekstrak etanol daun ketapang dengan zona hambat (p = 0,000) dan semakin tinggi konsentrasi ekstrak maka semakin besar zona hambat (r = 0,998). Dapat disimpulkan bahwa ekstrak etanol daun ketapang mempunyai efek sebagai antibakteri terhadap Staphylococcus aureus.
English Abstract
Staphylococcus aureus is a Gram-positive bacteria which often causes perineal wound infection and caesarean section wound infection on puerperal women. Nowadays, the existing antibacterial therapy has a high resistance against Staphylococcus aureus. Tropical almond leaves (Terminalia catappa) has active essence inside such as alkaloids, saponins, flavonoids, tannins, and quinones which are assumed the antibacterial activity takes place against Staphylococcus aureus. The aim of this study is to determine the effect of the ethanol extract of tropical almond leaves as an antibacterial against Staphylococcus aureus in vitro. This study is a laboratory experimental study using well diffusion method to determine the inhibition zone. Staphylococcus aureus samples derived from vaginal swab. Moreover, the concentration extracts used in this study are 60%, 50%, 40%, 30%, and 20% which results in inhibition zone respectively is 20,67 mm, 19,29 mm, 18,23 mm, 16,79 mm, and 15,26 mm. The result of One Way ANOVA test shows that there is a difference in the growth of Staphylococcus aureus significantly after giving the ethanol extract of tropical almond leaves (p = 0.000). The Pearson correlation test also shows that there is a significant relation between ethanol extract of tropical almond leaves with inhibition zone (p = 0.000) and the higher concentration of the extract make the greater of inhibition zone (r = 0,998). All in all, it can be concluded that the ethanol extract of tropical almond leaves has an effect as an antibacterial against Staphylococcus aureus.
| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | SKR/FK/2015/757/ 051600812 |
| Subjects: | 600 Technology (Applied sciences) > 618 Gynecology, obstetrics, pediatrics, geriatrics > 618.2 Obstetrics |
| Divisions: | Fakultas Kedokteran > Kebidanan |
| Depositing User: | Kustati |
| Date Deposited: | 11 Feb 2016 11:21 |
| Last Modified: | 26 Nov 2021 02:07 |
| URI: | http://repository.ub.ac.id/id/eprint/125562 |
Preview |
Text
125070601111004_COVER + DAFTAR ISI.pdf Download (195kB) | Preview |
Preview |
Text
125070601111004_BAB 5.pdf Download (451kB) | Preview |
Preview |
Text
125070601111004_BAB 3.pdf Download (87kB) | Preview |
Preview |
Text
125070601111004_Abstrak Ing+Ind.pdf Download (99kB) | Preview |
Preview |
Text
125070601111004_BAB 4.pdf Download (147kB) | Preview |
Preview |
Text
125070601111004_BAB 1.pdf Download (81kB) | Preview |
Preview |
Text
125070601111004_BAB 2.pdf Download (595kB) | Preview |
Actions (login required)
 |
View Item |