Setiawan, ChandraDewi (2015) Efektivitas Ekstrak Etanol Daun Lidah Mertua (Sansevieria trifasciata var. Laurentii) Sebagai Antibakteri Terhadap Streptococcus sanguis Secara In Vitro. Sarjana thesis, Universitas Brawijaya.
Abstract
Stomatitis Apthosa Recurrent adalah suatu penyakit mulut yang disebabkan oleh Streptococcus sanguis. Kasus resistensi Streptococcus sanguis terhadap antibiotik ditemukan di dunia dan timbul sebagai akibat penggunaan antibiotik yang tidak rasional. Oleh karena itu perlu dikembangkan alternatif pengobatan yang lebih efektif, efisien, dan dapat menurunkan biaya kesehatan tanpa melupakan standar mutu pelayanan medis. Tujuan dari penelitian ini untuk mengetahui efektivitas ekstrak etanol Daun Lidah Mertua sebagai antibakteri terhadap bakteri Streptococcus sanguis secara in vitro. Penelitian ini merupakan eksperimental laboratorik dengan metode dilusi tabung untuk mendapatkan nilai KHM dan KBM. Konsentrasi ekstrak etanol lidah mertua yang digunakan adalah 10%, 12,5%, 15%, 17,5%, 20% dan 22,5%. Hasil penelitian menunjukkan Kadar Hambat Minimum (KHM) diperoleh pada konsentrasi 17,5%, sedangkan Kadar Bunuh Minimum (KBM) pada konsentrasi 20%. Analisis data menggunakan oneway ANOVA menunjukkan adanya perbedaan yang signifikan pada perubahan konsentrasi ekstrak etanol lidah mertua terhadap jumlah koloni Streptococcus sanguis (p<0,05). Uji korelasi Pearson menunjukkan adanya hubungan yang kuat dan berbanding terbalik antara konsentrasi ekstrak etanol lidah mertua dengan jumlah koloni Streptococcus sanguis (R= -0,911). Uji regresi menunjukkan efektivitas ekstrak etanol lidah mertua terhadap Streptococcus sanguis sebesar 82,9%. Berdasarkan penelitian ini, dapat disimpulkan bahwa ekstrak etanol lidah mertua mempunyai efek antibakteri terhadap Streptococcus sanguis secara in vitro.
English Abstract
Stomatitis Aphtosa Recurrent is a oral pathology which is caused by Streptococcus sanguis. Resistance case of Streptococcus sanguis was found in the world and it is appear because of irrasional usage of antibiotics. This is the reason of the needs to develop alternative medical treatment which is more effective, efficient and can lowering health cost without forgetting quality standard of medical service. The purpose of this research is to know antibacterial effect of Mother in Law Tongue ethanolic extract for in vitro Streptococcus sanguis. This is a laboratory experimental study using tube dilution method to find MIC and MBC. The used concentration of ethanolic extract of mother in law tongue are 10%, 12,5%, 15%, 17,5%, 20% and 22,5%. The result showed the Minimum Inhibitory Concentration (MIC) is concentration of 17,5%, while the Minimum Bactericidal Concentration (MBC) is concentration of 20%. Analyzing oneway ANOVA showed a significant difference in the change of concentration of ethanolic extract of mother in law tongue on the number of colonies of Streptococcus sanguis (p <0.05). Pearson correlation test shows a strong and inversely relationship between the concentration of ethanolic extract of mother in law tongue and the number of colonies of Streptococcus sanguis (R= -0,911). Regression test showed the effectiveness of ethanolic extract of mother in law tongue against Streptococcus sanguis is 82,9%. Based on this study, it can be concluded that the ethanolic extract of mother in law tongue have antibacterial effects against Streptococcus sanguis in vitro
| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | SKR/FK/2015/217/051501660 |
| Subjects: | 600 Technology (Applied sciences) > 617 Surgery, regional medicine, dentistry, ophthalmology, otology, audiology > 617.6 Dentistry |
| Divisions: | Fakultas Kedokteran Gigi > Kedokteran Gigi |
| Depositing User: | Budi Wahyono Wahyono |
| Date Deposited: | 26 Feb 2015 11:05 |
| Last Modified: | 22 Oct 2021 07:25 |
| URI: | http://repository.ub.ac.id/id/eprint/124968 |
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