Fitriana, Anis (2014) Akurasi Pemeriksaan Potong Beku (Frozen Section) Di Instalasi Patologi Anatomi Rumah Sakit Dr. Saiful Anwar Malang Pada Pasien Tumor Ovarium Periode 2011-2013. Sarjana thesis, Universitas Brawijaya.
Abstract
Tumor ovarium merupakan penyebab kematian terbanyak akibat tumor ginekologi di dunia. Potong beku merupakan alat uji diagnostik yang dapat menentukan sifat tumor jinak maupun ganas dalam waktu yang singkat. Selain itu, potong beku dapat menjadi petunjuk dalam menentukan tindakan saat operasi. Penelitian ini dilakukan untuk menentukan akurasi pemeriksaan potong beku dalam penegakan diagnosa tumor ovarium di Instalasi Patologi Anatomi Rumah Sakit Dr. Saiful Anwar Malang periode Januari 2011-Desember 2013. Penelitian retrospektif dilakukan pada suspek neoplasma ovarium yang diperiksakan potong beku yang kemudian dibandingkan dengan hasil pemeriksaan parafin blok dan diukur akurasi, sensitivitas, spesifitas, nilai prediksi positif, serta nilai prediksi negatif. Pada pemeriksaan potong beku, ditemukan 334 kasus dengan 75,8% tumor jinak dan 24,2% kasus tumor ganas. Pada pemeriksaan parafin blok ditemukan 334 kasus dengan 74% kasus tumor jinak dan 26% kasus tumor ganas. Usia pasien berkisar antara 5 tahun hingga 80 tahun dengan rata-rata 40,2±12,6 tahun. Kasus tumor ovarium non-neoplastik terbanyak adalah endometriosis ovarii, kasus tumor ovarium jinak terbanyak adalah cystadenoma ovarii mucinosum, kasus tumor ovarium ganas terbanyak adalah cystadenocarcinoma ovarii mucinosum. Akurasi potong beku pada penelitian ini adalah 98,2% dengan sensitivitas 93,1%, spesifisitas 100%, nilai prediksi positif 100%, serta nilai prediksi negatif 97,6%. Dengan demikian, pemeriksaan potong beku dapat digunakan sebagai alat uji diagnostik yang akurat dalam penegakan diagnosa tumor ovarium intaoperatif.
English Abstract
Ovarian tumor is the heading source of death in gynecological tumors in the world. Frozen section is a diagnostic test tool that can determine the nature of benign and malignant tumors in a short time. In addition, frozen section can be a guidance in determining the actions in surgery. This study was conducted to determine the accuracy of frozen section examination in the diagnosis of ovarian tumors at Pathology Department of Dr. Saiful Anwar Malang Hospital period January 2011 until December 2013. A retrospective study was performed in suspected ovarian neoplasms that were examined by frozen section which is then compared with the results of the paraffin block examination and measured the accuracy, sensitivity, specificity, positive predictive value, and negative predictive value. In the frozen section examination, found 334 cases with 75.8% cases of benign tumors and 24.2% cases of malignant tumors. In the paraffin block examination, found 334 cases with 74% cases of benign tumors and 26% cases of malignant tumors. The age of patients ranged from 5 years to 80 years with an average of 40.2 ± 12.6 years. Most cases of non-neoplastic ovarian tumors are ovarian endometriosis, benign ovarian tumors are ovarian cystadenoma mucinosum, and most cases of malignant ovarian tumors are ovarian cystadenocarcinoma mucinosum. Accuracy of frozen section in this study was 98.2% with sensitivity 93.1%, specificity 100%, positive predictive value 100%, and negative predictive value 97.6%. Thus, frozen section examination can be used as an accurate diagnostic test tool in the intraoperative diagnosis of ovarian tumors.
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| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | SKR/FK/2014/725/051500548 |
| Uncontrolled Keywords: | potong beku, parafin blok, akurasi, tumor ovarium; frozen section, paraffin block, accuracy, ovarian tumor |
| Subjects: | 600 Technology (Applied sciences) > 616 Diseases > 616.9 Other disease > 616.99 Tumors and miscellaneous communicable diseases > 616.994 Cancers |
| Divisions: | Fakultas Kedokteran > Pendidikan Dokter |
| Depositing User: | Hasbi |
| Date Deposited: | 29 Jan 2015 14:14 |
| Last Modified: | 10 Dec 2021 03:15 |
| URI: | http://repository.ub.ac.id/id/eprint/124750 |
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