Rahmah, AliyahAdek (2014) Peran Elektro-Akupuntur Terhadap Perbedaan Kadar Interleukin-2 Pada Tikus Putih (Rattus Norvegicus) Galur Wistar Yang Diinduksi Dmba. Sarjana thesis, Universitas Brawijaya.
Abstract
Kanker Payudara Adalah Salah Satu Tumor Yang Bersifat Ganas Dan Merupakan Penyebab Kematian Utama Pada Wanita. Pada Penderita Kanker Payudara, Terjadi Penurunan Kadar Interleukin-2 (Il-2) Yang Berfungsi Sebagai Anti Kanker. Terapi Elektro-Akupuntur (Ea) Adalah Salah Satu Terapi Komplementer Yang Dapat Meningkatkan Kadar Interleukin-2 Pada Tubuh. Penelitian Ini Bertujuan Untuk Mengetahui Peran Elektro-Akupuntur Terhadap Perbedaan Kadar Interleukin-2 Pada Tikus Yang Diinduksi Dmba. Metode Penelitian Yang Digunakan Adalah True Experimental In Vivo, Dengan Sampel Tikus Wistar Berjumlah 25 Ekor. Sampel Dibagi Menjadi 5 Kelompok Perlakuan Yaitu (I) Kontrol Negatif (Kelompok Tikus Normal), (Ii) Kontrol Positif (Kelompok Tikus Yang Hanya Diberikan Induksi Dmba), (Iii) Perlakuan I (Kelompok Tikus Yang Diberikan Induksi Dmba Dan Terapi Ea Selama 3 Hari); (Iv) Perlakuan Ii (Kelompok Tikus Yang Diberikan Induksi Dmba Dan Terapi Ea Selama 5 Hari); (V) Perlakuan Iii (Kelompok Tikus Yang Diberikan Induksi Dmba Dan Terapi Ea Selama 10 Hari). Kadar Il-2 Diukur Menggunakan Metode Elisa Sandwich Dan Dianalisa Dengan One Way Anova Pada Spss 20. Hasil Penelitian Menunjukkan Rata-Rata Kadar Il-2 Terendah Terdapat Pada Tikus Kontrol Positif Dan Rata-Rata Kadar Il-2 Tertinggi Pada Tikus Perlakuan Ea 10 Hari. Hasil Uji Menunjukkan Terdapat Perbedaan Yang Bermakna Diantara Kelompok Perlakuan Terhadap Rata-Rata Kadar Il-2 (P = 0.000). Kesimpulan Yang Diperoleh Yaitu Terapi Elektro-Akupuntur Dapat Memberikan Perbedaan Kadar Il-2 Pada Tikus Yang Diinduksi Dmba.
English Abstract
Breast Cancer Is One Of Malignant Tumors And A Major Cause Of Death In Women. Breast Cancer Can Decrease Interleukin-2 That One Of The Functions Is To Resist The Cancer Cell. Electro-Acupuncture (Ea) Is A Kind Of Complementary Therapies Which Can Increase The Level Of Interleukin-2 (Il-2) In The Body. This Research Aims At Examining The Effect Of Electro-Acupuncture On The Difference Level Of Interleukin-2 In Rats Induced By Dmba. This Research Used True Experimental In Vivo And 25 Wistar Rats As A Sample. The Sample Were Divided Into 5 Groups: (I) Negative Control (Normal Rats); (Ii) Positive Control (Rats Which Were Induced By Dmba); (Iii) Treatment Group I (Rats Which Were Induced By Dmba And Given Ea Therapy For 3 Days); (Iv) Treatment Group Ii (Rats Which Were Induced By Dmba And Given Ea Therapy For 5 Days); (V) Treatment Group Iii (Rats Which Were Induced By Dmba And Given Ea Therapy For 10 Days). The Level Of Interleukin-2 Was Examined By Elisa Sandwich And Measured By One Way Anova On Spss 20. The Result Of This Research Shows The Minimum Level Of Il-2 Is In Negative Control Group And The Maximum Level Of Il-2 Is In Treatment Group Iii. Lsd Test Shows That There Is A Significant Difference Among Treatment Groups Towards Average Level Of Il-2 (P = 0.000). The Conclusion Of This Research Is That Electro-Acupuncture Therapy Can Make A Significant Difference In The Level Of Interleukin-2 In Rats Induced By Dmba.
| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | SKR/FK/2014/653/051407869 |
| Subjects: | 600 Technology (Applied sciences) > 610 Medicine and health > 610.7 Education, research, nursing, services of allied health personnel > 610.73 Nursing and services of allied health personnel |
| Divisions: | Fakultas Kedokteran > Ilmu Keperawatan |
| Depositing User: | Budi Wahyono Wahyono |
| Date Deposited: | 01 Dec 2014 14:38 |
| Last Modified: | 22 Oct 2021 04:00 |
| URI: | http://repository.ub.ac.id/id/eprint/124669 |
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