Hubungan Indeks Massa Tubuh (Imt) Dengan Respon Klinis Kemoradiasi Pasien Kanker Serviks Stadium Iii Di Rsud Dr. Saiful Anwar Malang

Werestandina, Adys (2014) Hubungan Indeks Massa Tubuh (Imt) Dengan Respon Klinis Kemoradiasi Pasien Kanker Serviks Stadium Iii Di Rsud Dr. Saiful Anwar Malang. Sarjana thesis, Universitas Brawijaya.

Abstract

Kanker serviks merupakan gangguan yang terjadi pada sel somatik, ketika perubahan materi genetik menyebabkan sel normal berperilaku abnormal. Pada kanker serviks stadium III dilakukan pengobatan standart yaitu kemoradiasi. Respon klinis kemoradiasi dipengaruhi beberapa faktor salah satunya yaitu Indeks Massa Tubuh (IMT). Penelitian ini bertujuan mengetahui hubungan indeks massa tubuh dengan respon klinis kemoradiasi pasien kanker serviks stadium III. Desain penelitian observasi dengan pendekatan cohort retrospective menggunakan data rekam medis pasien kanker serviks di RSUD dr. Saiful Anwar Malang. Data rekam medis yang digunakan adalah 27. Dilakukan uji korelasi spearman’s rho, didapatkan hubungan yang signifikan antara indeks massa tubuh terhadap respon klinis kemoradiasi dengan p-Value 0.001 dimana nilai p-Value lebih kecil dari α=0.05. Uji hubungan keeratan dengan Correlation Coefficient didapatkan hasil -0.594, yang berarti bahwa ada hubungan yang kuat antara IMT dengan respon klinis. Nilai negatif menerangkan bahwa ada hubungan yang berkebalikan antara IMT dengan respon klinis.

English Abstract

Cervical cancer is a disorder that occurs in somatic cells, when the change of genetic material causes normal cells to behave abnormally. In stage III of cervical cancer need standard treatment named chemoradiation. The response of this therapy is influenced by several factors, one of them is Body Mass Index (BMI). This study aims to determine the relationship of body mass index with clinical response to chemoradiation of stage III of cervical cancer patients in Dr. Saiful Anwar Public Hospital of Malang. The design of study was observational with cohort retrospective using medical record of cervical cancer patients in Dr. Saiful Anwar Public Hospital of Malang. The medical record data used was 27. The data performed by spearman’s rho test. There is a significant correlation between BMI and clinical response to chemoradiation with p-Value 0.001 (0.001 < α=0.05). Correlation test with Correlation Coefficient find result -0.594, there is strong correlation between BMI and clinical response to chemoradiation. The meaning of Negative value that inverse correlation between BMI and clinical response to chemoradiation.

Item Type: Thesis (Sarjana)
Identification Number: SKR/FK/2014/315/051402971
Subjects: 600 Technology (Applied sciences) > 618 Gynecology, obstetrics, pediatrics, geriatrics > 618.2 Obstetrics
Divisions: Fakultas Kedokteran > Kebidanan
Depositing User: Budi Wahyono Wahyono
Date Deposited: 30 May 2014 13:43
Last Modified: 21 Oct 2021 09:30
URI: http://repository.ub.ac.id/id/eprint/124298
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