Christianto, AdhiarBagus (2014) Pengaruh Pemberian Ekstrak Jahe Emprit (Zingiber officinale var. Amarum) dalam Meningkatkan Proses Kontraksi Luka Terkontaminasi pada Tikus Putih (Rattus norvegicus) Galur Wistar. Sarjana thesis, Universitas Brawijaya.
Abstract
Kejadian luka terkontaminasi sering disebabkan oleh kecelakaan lalu lintas. Obat tradisional lebih mudah diterima oleh masyarakat. Jahe emprit mengandung oleoresin, minyak atsiri dan flavonoid yang berfungsi sebagai antiinflamasi, antimikroba dan antioksidan. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak jahe emprit (Zingiber officinale var. Amarum) dalam meningkatkan proses kontraksi luka terkontaminasi pada tikus putih (Rattus norvegicus) galur wistar. Penelitian ini merupakan penelitian True Experimental dengan desain penelitian Pretest and Posttest Control Group Design. Penelitian ini terdiri dari 4 kelompok yaitu 1 kelompok kontrol menggunakan povidone iodine 10% dan 3 kelompok perlakuan menggunakan ekstrak jahe emprit 5%, 20% dan 35%. Variabel yang diukur kontraksi luka menggunakan rumus % of wound contraction pada hari ke-4, 6, 8, 10 dan 12. Analisa data One way ANOVA menunjukkan proses kontraksi luka berbeda signifikan p = 0,036 < α (0,05) pada hari ke-10 dan p = 0,006 < α (0,05) pada hari ke-12. Dilanjutkan uji Tukey HSD ada perbedaan yang signifikan antara kelompok kontrol povidone iodine 10% dengan kelompok perlakuan ekstrak jahe emprit 5% pada hari ke-10 dengan p = 0,049 < α (0,05) dan ke-12 dengan p = 0,010 < α (0,05). Ada perbedaan yang signifikan antara kelompok perlakuan ekstrak jahe emprit konsentrasi 20% dengan ekstrak jahe emprit konsentrasi 5%, p = 0,012 < α (0,05). Kesimpulan penelitian povidone iodine 10% mempunyai pengaruh yang paling optimal dalam meningkatkan kontraksi luka terkontaminasi. Ekstrak jahe emprit 20% memiliki efek yang sama bagusnya dengan povidone iodine 10% dalam meningkatkan kontraksi luka terkontaminasi.
English Abstract
Incidence of contaminated wounds are often caused by traffic accidents. Traditional medicine is more easily accepted by the people. Ginger contains oleoresins, essential oils and flavonoids that function as anti-inflammatory, antimicrobial and antioxidant. This study aims to determine the effect of ginger extract (Zingiber officinale var. Amarum) to increase the wound contraction process of contaminated wound in white rats (Rattus norvegicus) wistar strain. This study is True Experimental with Pretest and Posttest Control Group Design. The study consisted of four groups: one control group using povidone iodine 10% and 3 treatment groups using ginger extract 5%, 20% and 35%. Variables were measured wound contraction using the formula % of wound contraction on day 4th , 6th, 8th ,10th and 12th. One way ANOVA analysis of the data shows the process of wound contraction significantly different with p = 0,036 < α (0,05) on day 10 and p = 0,006 < α (0,05) on day 12. Tukey HSD test were significant difference between control group povidone iodine 10% with treatment group ginger extract concentration of 5% on day 10th with p = 0,049 < α (0,05) and on day 12th with p = 0,010 < α (0,05). There are significant differences between treatment group ginger extract concentration of 20% with ginger extract concentration of 5%, p = 0,012 < α (0,05). Study conclusion povidone iodine 10% have most optimal influence to increase wound contraction process of contaminated wound. Ginger extract concentration of 20% have the same effect with povidone iodine 10% to increase wound contraction process of contaminated wound.
| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | SKR/FK/2014/277/051402933 |
| Subjects: | 600 Technology (Applied sciences) > 610 Medicine and health > 610.7 Education, research, nursing, services of allied health personnel > 610.73 Nursing and services of allied health personnel |
| Divisions: | Fakultas Kedokteran > Ilmu Keperawatan |
| Depositing User: | Budi Wahyono Wahyono |
| Date Deposited: | 28 May 2014 11:17 |
| Last Modified: | 21 Oct 2021 09:03 |
| URI: | http://repository.ub.ac.id/id/eprint/124255 |
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