Upaya pengendalian ekspresi mirna yang menghambat diferensiasi sel stem hematopoietic menjadi eritrosit sebagai alternatif obat anemia

Djati, Moch.Sasmito and -, Muhaimin and -, Widodo (2010) Upaya pengendalian ekspresi mirna yang menghambat diferensiasi sel stem hematopoietic menjadi eritrosit sebagai alternatif obat anemia. Project Report. Lembaga Pengabdian Kepada Masyarakat Universitas Brawijaya, Malang. (Unpublished)

Abstract

Erythropoietic is the formation processes from stem cells became erythrocytes; this processes were started from multi-potentially un-fate cells (hematopoietic stem cell/HSCs). from that cell will be differentiated becoming uni-potential cellular, one differentiated cells was erythrocyte. tapak liman (Elephantopus scaber L) were used to activating Erythropoietic on hematopoietic stem cells. hematopoietic stem cells were obtained from mouse bone marrow. out, 250 ul,500 ui, 750 ml and 1000 µl of tapak liman,crude extract were solved on TCM 199 with 10% FBS (feurtai bovine serum). This solution was used for Hematopuietic stem cells culture medium.HSCs were culture for -12 days and 48 hours medium exchange, they were incubated on CO2 5%, 37°C and maximum humidity. the result of the experiment show that the crude exracts from stem, leaf, and root of tapak liman giving no differential effected to activating the arythropuietic processes between them, but all of them giving positive impact to activating arythropuietic processes comparing control.

Item Type: Monograph (Project Report)
Identification Number: PEN/616.152/UPA/u/2010/021100191
Subjects: 600 Technology (Applied sciences) > 616 Diseases > 616.1 Diseases of cardiovascular system > 616.15 Diseases of blood > 616.152 Anemia
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam > Biologi
Depositing User: Yusuf Dwi N.
Date Deposited: 13 Sep 2018 02:44
Last Modified: 20 Sep 2018 03:44
URI: http://repository.ub.ac.id/id/eprint/11942
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