Widiasi, DhantiErma (2014) Kesesuaian MRI 1,0 Tesla untuk Membedakan Spondilitis dan Metastasis Vertebra dengan Konfirmasi Hasil Histopatologi. Magister thesis, Universitas Brawijaya.
Abstract
Latar Belakang : Magnetic Resonance Imaging (MRI) merupakan modalitas imaging yang akurat dalam menilai vertebra dan kelainannya. Infeksi dan metastasis di muskuloskeletal paling sering didapatkan pada vertebra. Sulit untuk membedakan kedua kelainan tersebut secara klinis maupun imaging terutama pada kasus atypical. Tujuan : Menganalisa kesesuaian MRI 1,0 Tesla untuk membedakan gambaran radiologis spondilitis dan metastasis vertebra dengan konfirmasi hasil histopatologi. Metode : Studi observasional analitik, desain penelitian cross- sectional . Analisis statistik menggunakan metode Mc Nemar. Sampel dipilih secara consecutive dengan jumlah 35 (15 laki-laki, 20 perempuan), terdiri dari 22 sampel spondilitis dan 13 sampel metastasis yang telah dikonfirmasi dengan pemeriksaan histopatologi. Hasil : 22 sampel dengan histopatologi spondilitis sebanyak 86% (19 sampel) terdiagnosis sebagai spondilitis pada MRI, sedangkan dari 13 sampel metastasis 100% terdiagnosis dengan benar pada MRI. Kesimpulan : Secara statistik tidak ada perbedaan bermakna antara diagnosis radiologi menggunakan MRI 1,0 Tesla dengan diagnosis histopatologi p=0,250 (p 0,05), dengan kecenderungan MRI 1,0 Tesla lebih tepat dalam mendiagnosis metastasis. Gambaran MRI yang khas untuk spondilitis yaitu keterlibatan komponen anterior vertebra dan diskus intervertebralis, penyangatan diskus, abses paravertebra serta keterlibatan segmen vertebra berurutan. Gambaran MRI khas untuk metastasis yaitu keterlibatan komponen anterior posterior vertebra, massa paravertebralis dan skip lesion .
English Abstract
Background : Magnetic Resonance Imaging (MRI) are most accurate modality imaging to evaluate vertebral abnormality. Infection and metastatic in musculoskeletal most commonly found in vertebra. It is often difficult to differentiate between spondylitis and metastatic, both clinically and radiographicly mainly on a typical case. Objective : To a nalyze precision of MRI 1,0 Tesla in differentiate radiological imaging between spondylitis and vertebral metastatic with histopathological confirmation. Materials and methods : Analytic observational study, with cross-sectional research design. Statistical analysis was performed with Mc Neemar test. Samples were selected by consecutive sampling with 35 patients (15 men, 20 women), 22 samples of spondylitis and 13 of samples metastatic which were confirmed by histopathological examination. Result : 22 samples spondylitis by histopathology, only 86% (19 samples) were diagnosed as having spondylitis on MRI, whereas 13 metastatic samples 100% was correctly diagnosed on MRI. Conclusion : Statistically re was no significant differences between radiology diagnostic using 1.0 Tesla MRI with histopathological diagnosis, p=0,250 (p 0,05), with tendency MRI 1.0 Tesla is more precise in diagnosing metastatic. MR images show typical findings in spondylitis such as anterior component corpus vertebral and discus intervertebralis involvement, disk signal abnormalities, paravertebral abscesses and involvement of multiple vertebral bodies sequentially . MR images show typical findings in metastasis such as anterior and posterior corpus vertebral involvement, paravertebral soft tissue mass and skip lesion.
| Item Type: | Thesis (Magister) |
|---|---|
| Identification Number: | TES/616.075 48/WID/k/041403637 |
| Subjects: | 600 Technology (Applied sciences) > 616 Diseases |
| Divisions: | Profesi Kedokteran > Spesialis Radiologi, Fakultas Kedokteran |
| Depositing User: | Endro Setyobudi |
| Date Deposited: | 02 Sep 2014 15:52 |
| Last Modified: | 02 Sep 2014 15:52 |
| URI: | http://repository.ub.ac.id/id/eprint/158248 |
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