SanjataPanduPutraHaryuDharma (2013) Perbandingan Efektivitas Antifungal Ekstrak Maserasi dan Soxhletasi Bunga Kembang Sepatu (Hibiscus rosa sinensis L.) terhadap Pertumbuhan Candida albicans secara In Vitro. Sarjana thesis, Universitas Brawijaya.
Abstract
Candida albicans is a fungus species that are normally present in the human oral cavity. Candida albicans is an opportunistic pathogen that is not harm in healthy individuals but it will be a pathogen in individuals with weak immune condition. According to the literature, hibiscus flower can be used for the treatment of various infectious diseases. However, research on the effects of hibiscus flower antifungal against Candida albicans is still lacking, especially in comparison method extracts of maceration and soxhletation to determine the most effective extraction techniques in dissolving the active material of hibiscus flowers. Hibiscus flower contains an active ingredient calls flavonoid that is thought to have antifungal effects. This study aims to compare the effects of antifungal maceration extract and hibiscus soxhletasi against Candida albicans by using a tube dilution assay followed by etching on SDA medium so they can know a better method extracts the maceration method and soxhlet. Candida albicans isolate were derived from Microbiology Laboratorium of Brawijaya University’s Medical Faculty. Statistical test results showed that there were differences in the mean number of colonies were significantly (p <0.05) between the results of the extracts maceration and soxhletasi method where the number of colonies of Candida albicans in soxhlet method is always less than the maceration method. In conclusion, Hibiscus flower’s extract using soxhlet has a stronger antifungal efficacy against Candida albicans with the Minimum Fungicidal Concentration (MFC) is 30% than using maceration method with the Minimum Fungicidal Concentration (MFC) is 38%. While the Minimum Inhibitory Concentration (MIC) cannot be detected
| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | SKR/FK/2013/231/051303532 |
| Subjects: | 600 Technology (Applied sciences) > 616 Diseases > 616.9 Other disease > 616.96 Parasitic diseases and diseases due to fungi (mycoses) / Medical parasitology |
| Depositing User: | Hasbi |
| Date Deposited: | 30 Apr 2013 14:39 |
| Last Modified: | 13 Oct 2020 03:03 |
| URI: | http://repository.ub.ac.id/id/eprint/123518 |
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