Wardhana, Donny Wisnu and Prof.Dr.dr. Nurdiana, M.Kes and Dr.med dr. Tommy Alfandy Nazwar, SpBS(K) and Dr. Husnul Khotimah, S.Si., M.Kes (2024) Peran Minosiklin Dalam Menghambat Pembentukan Glial scar Melalui Ekspresi CNTF, TGF-β1, dan NF-κB p65 Pada Tikus Model Cedera Otak Traumatik. Doktor thesis, Universitas Brawijaya.
Abstract
Cedera otak traumatik menyebabkan angka kematian dan kecacatan tinggi pada masyakat umur muda dan produktif baik di seluruh dunia termasuk di Indonesia yang mayoritas diakibatkan kecelakan kendaraan bermotor. Walaupun angka kematian mulai bisa ditekan disebabkan makin baiknya sistem tatalaksana trauma dan teknologi keselamatan pada kendaraan bermotor, tetapi angka kecacatan berupa gangguan neurobehavioral menetap pascacedera otak masih tetap tinggi dan belum ada pengobatan yang efektif, sehingga menimbulkan permasalahan untuk negara, keluarga, individu dan lingkungan pasien.
English Abstract
Traumatic brain injury causes high mortality and disability rates in young and productive people around the world, including in Indonesia, the majority of which are caused by motor vehicle accidents. Although the death rate is starting to be reduced due to the improvement in the trauma management system and safety technology for motorized vehicles, the rate of disability in the form of permanent neurobehavioral disorders after brain injury is still high and there is no effective treatment, causing problems for the country, families, individuals and the patient’s environment.
| Item Type: | Thesis (Doktor) |
|---|---|
| Identification Number: | 0624060004 |
| Uncontrolled Keywords: | cedera otak traumatik, glial scar, minosiklin, GFAP, CNTF, TGF-β1, NF-κB p65 |
| Divisions: | S2/S3 > Doktor Ilmu Kedokteran, Fakultas Kedokteran |
| Depositing User: | Unnamed user with email dini@ub.ac.id |
| Date Deposited: | 02 Apr 2024 01:56 |
| Last Modified: | 02 Apr 2024 01:56 |
| URI: | http://repository.ub.ac.id/id/eprint/217799 |
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Text (DALAM MASA EMBARGO)
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