Analisis Kuantitatif Penggunaan Antibiotika di Beberapa Puskesmas Rawat Jalan Wilayah Kabupaten Malang Tahun 2020- 2021

Ulimazaim, Salmadiar Riska and apt. Ayuk Lawuningtyas Hariadini, S.Farm., M.Farm and apt. Arsy Arundina, S.Farm, MMRS (2023) Analisis Kuantitatif Penggunaan Antibiotika di Beberapa Puskesmas Rawat Jalan Wilayah Kabupaten Malang Tahun 2020- 2021. Sarjana thesis, Universitas Brawijaya.

Abstract

Tingginya prevalensi infeksi di Kabupaten Malang tahun 2020 menyebabkan peningkatan peresepan antibiotik di Puskesmas. Peningkatan penggunaan antibiotik mengakibatkan tingginya kasus resistensi sehingga diperlukan analisis penggunaan antibiotik. Analisis dilakukan untuk mengetahui antibiotik yang diresepkan, diagnosis yang memerlukan antibiotik dan frekuensi peresepan antibiotik. Analisis penggunaan antibiotik dilakukan secara kuantitatif menggunakan metode Anatomical Therapeutic Classification/ Defined Daily Dose (ATC/DDD), Drug Utilization (DU 90%) dan nilai DDD/1000 pelayanan resep. DU 90% adalah peresepan antibiotik tertinggi 90%, DDD/1000 menggambarkan jumlah kunjungan pasien penerima antibiotik tiap 1000 pelayanan resep. Tujuan penelitian ini untuk mengevaluasi penggunaan antibiotik secara deskriptif di Puskesmas Kabupaten Malang tahun 2020-2021. Penelitian dilakukan secara analitik menggunakan total sampling data rekam medis e�Puskesmas di 9 puskesmas Kabupaten Malang tahun 2020-2021 sesuai kriteria inklusi dan eksklusi yang telah ditetapkan. Dari 103996 data peresepan obat di puskesmas, 17271 data merupakan peresepan antibiotik. Penggunaan antibiotik tertinggi (DU 90%) tahun 2020 adalah Amoxicillin, Ciprofloxacin, Sulfamethoxazole dan trimethoprim (Cotrimoxazole), Cefadroxil, dan Clindamycin, sedangkan tahun 2021 adalah Amoxicilin, Azithromycin, Ciprofloxacin, Cefadroxil, Clindamycin, dan Metronidazole. Frekuensi peresepan antibiotik tertinggi adalah Amoxicillin. Data DDD/1000 pasien tahun 2020 dibandingkan dengan tahun 2021 menggunakan uji wilcoxon (p=0,910) karena tidak terdistribusi normal. Dari penelitian ini, didapatkan perbedaan jenis peresepan antibiotik tertinggi 90% (DU90%) antara tahun 2020-2021 di beberapa Puskesmas Kabupaten Malang, yaitu menurunnya peresepan Cotrimoxazole dan meningkatnya peresepan Azithromycin dan Metronidazole. Namun, tidak terdapat perbedaan yang signifikan antara jumlah peresepan antibiotik setiap 1000 pelayanan resep (DDD/1000) pada tahun 2020-2021 di pelayanan rawat jalan beberapa Puskesmas Kabupaten Malang.

English Abstract

The high prevalence of infections in Malang Regency in 2020 led to an increase in antibiotic prescribing at Community Health Centers. The increasing use of antibiotics has resulted in high cases of resistance, so analysis of antibiotic use is needed. Analysis was carried out to determine antibiotics prescribed, diagnoses requiring antibiotics, and frequency of antibiotic prescriptions. Antibiotic use was analyzed quantitatively using the Anatomical Therapeutic Classification/Defined Daily Dose (ATC/DDD), Drug Utilization (DU 90%), and DDD/1000 prescription services methods. DU 90% represents the highest 90% of antibiotic prescriptions, and DDD/1000 describes the number of recipient patient visits per 1000 antibiotic prescription services. This study aims to determine descriptively the distribution of antibiotic use in Malang Regency Health Centers in 2020-2021. The research was conducted analytically using total sampling of e-Puskesmas medical record data at 9 Malang Regency Health Centers in 2020- 2021 according to predetermined inclusion and exclusion criteria. 103996 data on drug prescriptions at Community Health Centers, 17271 were antibiotic prescriptions. The highest antibiotic use (DU 90%) in 2020 was Amoxicillin, Ciprofloxacin, Sulfamethoxazole and trimethoprim (Cotrimoxazole), Cefadroxil, and Clindamycin, while in 2021 it was Amoxicillin, Azithromycin, Ciprofloxacin, Cefadroxil, Clindamycin, and Metronidazole. The highest frequency of antibiotic prescription is Amoxicillin. DDD/1000 patient data in 2020 was compared with 2021 using the Wilcoxon test (p=0.910) because it was not normally distributed. From this research, it was found that the highest difference in types of antibiotic prescriptions was 90% (DU90%) between 2020-2021 in several Malang District Health Centers, namely a decrease in Cotrimoxazole prescriptions and an increase in Azithromycin and Metronidazole prescriptions. However, there is no significant difference between the number of antibiotic prescriptions per 1000 prescription services (DDD/1000) in 2020-2021 in outpatient services in several Malang Regency Health Centers.

Item Type:	Thesis (Sarjana)
Identification Number:	052306
Uncontrolled Keywords:	Antibiotik, ATC/DDD, DU 90%, DDD/1000
Divisions:	Fakultas Kedokteran > Farmasi
Depositing User:	Endang Susworini
Date Deposited:	23 Feb 2024 04:00
Last Modified:	23 Feb 2024 04:00
URI:	http://repository.ub.ac.id/id/eprint/216194

Text (DALAM MASA EMBARGO) Salmadiar Riska Ulimazaim.pdf Restricted to Registered users only Download (5MB)

Actions (login required)

View Item