Bakhtiar, Fakhruddin Adi and dr. Niniek Budiarti, Sp.PD, KPTI and dr. Herwindo Pudjo Brahmantyo, Sp.PD, KHOM (2024) Hubungan Antara Kadar Cluster Of Differentiation 4 (CD4) Dengan Kondisi Leukopenia Pada Tingkat Keparahan HIV Pada Pasien Human Immunodeficiency Virus (HIV) Naif di RSUD DR. Saiful Anwar Malang. Sarjana thesis, Universitas Brawijaya.
Abstract
Pendahuluan: Human Immunodeficiency Virus (HIV) adalah virus yang menyerang sistem imun khususnya pada sel CD4. Penurunan kadar CD4 secara signifikan kemudian menimbulkan kondisi acquired immunodeficiency syndrome (AIDS). Hingga kini masih minim data terkait hubungan antara HIV pada kadar CD4 serta kaitannya dengan leukopenia. Tujuan: Mengetahui hubungan antara kadar CD4 pada pasien HIV naif serta tingkat keparahan HIV dengan kondisi leukopenia di RSUD Dr. Saiful Anwar Malang. Metode: Penelitian analitik observasional dengan pendekatan cross sectional ini melibatkan tiga variabel, yaitu kadar CD4, kejadian Leukopenia, serta stadium HIV pada pasien HIV naif di RSUD Dr. Saiful Anwar Malang. Sampel pada penelitian ini berjumlah 40 orang. Adapun Pengumpulan data subjek penelitian berasal dari poliklinik pasien HIV naif di Rumah Sakit Umum Daerah Dr. Saiful Anwar Malang pada periode bulan Januari 2022 hingga Oktober tahun 2023. Data penelitian dianalisis secara deskriptif serta dilakukan uji komparatif. Hasil dan Pembahasan: Dapat diketahui bahwa kadar CD4 pada subjek penelitian ini median 205,5. Didapatkan nilai dari uji Mann-Whitney dengan tingkat signifikansi 0,281. Berdasarkan tingkat signifikansinya, dapat diketahui bahwa kadar CD4 tidak berhubungan dengan kondisi leukopenia karena tingkat signifikansinya lebih dari 0,05. Kesimpulan: Tidak didapatkan hubungan antara kadar Cluster of differentiation 4 (CD4) dengan kondisi leukopenia pada pasien Human Immunodeficiency virus (HIV) naif di RSUD Dr. Saiful Anwar.
English Abstract
Introduction: HIV is a virus that particularly targets CD4 cells,within the immune system. A significant decrease in CD4 levels then causes the condition of acquired immunodeficiency syndrome (AIDS). However, there is still lack of data regarding the relationship between HIV, especially CD4 levels and its relationship with leukopenia. Aims: To determine the relationship between CD4 levels in naive HIV patients and the severity of HIV and the condition of leukopenia at RSUD Dr. Saiful Anwar Malang. Method: This observational analytical study with a cross sectional approach involved three variables, namely CD4 levels, the incidence of Leukopenia, and HIV stage in HIV naïve patients at RSUD Dr. Saiful Anwar Malang. The sample used in this research was 40 people. The research subject data collection came from examinations at the polyclinic for naive HIV patients at the Dr. Regional General Hospital. Saiful Anwar Malang in the period January 2022 to October 2023. The research data was then analyzed descriptively, and a comparative test was carried out using the chi square test. Results and Discussion: The median of CD4 levels in the subjects of this study were 205,5. with a significance level of 0.281. Based on the significance level, CD4 levels are not related to leukopenia because the significance level is more than 0.05. Conclusion: There was no relationship between Cluster of differentiation 4 (CD4) levels and leukopenia in naïve Human Immunodeficiency Virus (HIV) patients at RSUD Dr. Saiful Anwar.
| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | 0524060091 |
| Uncontrolled Keywords: | CD4, Leukopenia, HIV, Tingkat Keparahan |
| Divisions: | Fakultas Kedokteran > Pendidikan Dokter |
| Depositing User: | Endang Susworini |
| Date Deposited: | 21 Feb 2024 03:13 |
| Last Modified: | 21 Feb 2024 03:13 |
| URI: | http://repository.ub.ac.id/id/eprint/215935 |
![[thumbnail of DALAM MASA EMBARGO]](http://repository.ub.ac.id/style/images/fileicons/text.png) |
Text (DALAM MASA EMBARGO)
Fakhruddin Adi Bakhtiar.pdf Restricted to Registered users only Download (2MB) |
Actions (login required)
 |
View Item |