Andriyani, Fanny Rizky (2019) Perbedaan Fase Kristal Membran Komposit Nano Hydroxyapatite-Magnesium Oxide (nHA-MGO) dengan Hydroxyapatite-Magnesium Oxide (HA-MGO) Melalui Uji X-Ray Diffraction (XRD). Sarjana thesis, Universitas Brawijaya.
Abstract
Periodontitis merupakan salah satu penyakit periodontal yang dapat menyebabkan hilangnya perlekatan dan turunnya tulang alveolar. Terapi yang telah digunakan adalah Guided Tissue Regeneration (GTR). Salah satu syarat dari biomaterial pada GTR adalah memiliki sifat biodegradasi. Biodegradasi yang tinggi ditandai dengan derajat kristalinitas yang rendah. Hydroxyapatite (HA) merupakan bahan yang sering digunakan pada GTR yang dapat membantu regenerasi jaringan dan tulang serta memiliki sifat biodegradasi. Hydroxyapatite (HA) memiliki kelemahan yaitu bersifat rapuh. Pada penelitian sebelumnya penambahan Magnesium Oxide (MgO) dapat meningkatkan sifat mekanis HA. Selain itu pada material dengan skala nanometer memiliki sifat mekanis yang lebih baik. Penelitian ini bertujuan untuk mengetahui perbedaan derajat kristalinitas antara membran komposit nHA-MgO dengan membran komposit HA-MgO. Membran komposit dengan penambahan MgO 2 wt% dibuat dengan metode freeze drying yang kemudian dilakukan uji karakterisasi X-Ray Diffraction (XRD). Dari hasil analisis diketahui ukuran kristal membran komposit HA-MgO dan membran komposit nHA-MgO adalah sebesar 51,42 nm dan 48,98 nm. Berdasarkan puncak difraksi, membran komposit nHA-MgO memiliki derajat kristalinitas yang lebih rendah dibandingkan membran komposit HA-MgO sehingga mengindikasikan degradasi pada membran komposit nHA-MgO lebih tinggi dibandingkan membran komposit HA-MgO.
English Abstract
Periodontitis is one of periodontal disease that caused loss of attachment and alveolar bone decrease. Treatment that has been used in periodontitis is Guided Tissue Regeneration (GTR). Biomaterial in GTR is require to have a capability of biodegradation. High biodegradation capibility is indicated by low degree of crystallinity. Hydroxyapatite (HA) is a common biomaterial that has been used in GTR. HA helps the process of tissue and bone regeneration and also has a capability of biodegradation. But HA has a disadvantage which is brittle. In previous studies, MgO has been reported to improve the mechanical properties of HA and also there is a mechanical properties improvement in nanoscale material. The aim of this study was to evaluate the difference of crystallinity degree between Nano Hydroxyapatite-Magnesium Oxide (nHA-MgO) composite membrane and Hydroxyapatite-Magnesium Oxide (HA-MgO) composite membrane. The composite membrane in this study was added by 2 wt% of MgO. The composite membrane has been synthesized with Freeze Drying method and characterized with X-Ray Diffraction (XRD). From the results of this study, crystalline size of HA-MgO composite membrane and nHA-MgO composite membrane were found to be 51.42 nm and 48.98 nm. It is apparance that the crystallinity degree of nHA-MgO composite membrane is lower then HA-MgO composite membrane, which indicates that nHA-MgO membrane has higher capability of biodegradation than HA-MgO composite membrane.
| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | SKR/FKG/2019/133/052001895 |
| Uncontrolled Keywords: | Nano Hydroxyapatite, Magnesium Oxide, freeze drying, X-Ray Diffraction, derajat kristalinitas-Nano Hydroxyapatite, Magnesium Oxide, freeze drying, X-Ray Diffraction, degree of crystallinity. |
| Subjects: | 600 Technology (Applied sciences) > 617 Surgery, regional medicine, dentistry, ophthalmology, otology, audiology > 617.7 Ophthalmology > 617.702 85 Ophthalmology (Computer applications) |
| Divisions: | Fakultas Kedokteran Gigi > Kedokteran Gigi |
| Depositing User: | soegeng sugeng |
| Date Deposited: | 10 Aug 2020 07:50 |
| Last Modified: | 23 Oct 2021 02:19 |
| URI: | http://repository.ub.ac.id/id/eprint/179054 |
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