Rani, Desy Puspa (2019) Perbandingan Daya Antibakteri Ekstrak Etanol Daun Seledri (Apium graveolens L.) dan Chlorhexidine Terhadap Pertumbuhan Aggregatibacter actinomycetemcomitans Dengan Metode Difusi Sumuran. Sarjana thesis, Universitas Brawijaya.
Abstract
Penyakit periodontal merupakan penyakit rongga mulut yang menempati urutan kedua di Indonesia. Periodontitis agresif sering dikaitkan dengan bakteri patogen, salah satu bakteri patogen dominan penyebab periodontitis agresif adalah Aggregatibacter actinomycetemcomitans. Daun seledri (Apium graveolens L.) mengandung fenol, alkaloid, flavonoid, saponin, tanin dan triterpenoid yang mampu menghambat pertumbuhan bakteri Aggregatibacter actinomycetemcomitans. Sedangkan chlorhexidine mampu mencegah terjadinya penyakit periodontal dikarenakan sifatnya yang bakterisid dan bakteriostatik terhadap berbagai macam bakteri. Penelitian ini bertujuan untuk membuktikan bahwa daun seledri (Apium graveolens L.) dapat menandingi daya antibakteri chlorhexidine terhadap pertumbuhan bakteri Aggregatibacter actinomycetemcomitans dengan metode difusi sumuran. Perlakuan dibagi menjadi 4 kelompok (70%, 80%, 90%, 100%), chlorhexidine, dan kontrol negatif (aquades steril). Hasil uji statistika menunjukkan terdapat perbedaan bermakna pada setiap konsentrasi ekstrak daun seledri (One-Way ANOVA, p=0,000) dan terdapat hubungan yang bermakna antara konsentrasi ekstrak daun seledri yang diberikan terhadap diameter zona hambat pertumbuhan bakteri (Pearson, correlation coefficient = 0,862). Kesimpulan penelitian ini adalah ekstrak daun seledri (Apium graveolens L.) tidak dapat menandingi daya antibakteri chlorhexidine terhadap pertumbuhan bakteri Aggregatibacter actinomycetemcomitans.
English Abstract
Periodontal disease is an oral disease that ranks second in Indonesia. Aggressive periodontitis is often associated with pathogenic bacteria, one of the dominant pathogenic bacteria causing aggressive periodontitis is Aggregatibacter actinomycetemcomitans. Celery leaves (Apium graveolens L.) contain phenols, alkaloids, flavonoids, saponins, tannins and triterpenoids which can inhibit the growth of Aggregatibacter actinomycetemcomitans. While chlorhexidine is able to prevent periodontal disease due to its bactericidal and bacteriostatic properties of various types of bacteria. This study aims to prove that celery leaves (Apium graveolens L.) can match the antibacterial power of chlorhexidine to the growth of Aggregatibacter actinomycetemcomitans with well diffusion method. The treatment was divided into 4 groups (70%, 80%, 90%, 100%), chlorhexidine, and negative controls (sterile distilled water). The results of statistical tests showed significant differences in each concentration of celery leaf extract (One-Way ANOVA, p = 0,000) and there was a significant relationship between the concentration of celery leaf extract given to the diameter of the inhibition zone of bacterial growth (Pearson, correlation coefficient = 0,862). The conclusion of this study is that celery leaf extract (Apium graveolens L.) cannot match the antibacterial power of chlorhexidine to the growth of Aggregatibacter actinomycetemcomitans.
| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | SKR/FKG/2019/124/052001886 |
| Uncontrolled Keywords: | Aggregatibacter actinomycetemcomitans, chlorhexidine, ekstrak daun seledri, periodontitis agresif, zona hambat Aggregatibacter actinomycetemcomitans, chlorhexidine, celery leaf extract, aggressive periodontitis, inhibition zone. |
| Subjects: | 600 Technology (Applied sciences) > 617 Surgery, regional medicine, dentistry, ophthalmology, otology, audiology > 617.6 Dentistry > 617.66 Extraction / Teeth--Extraction |
| Divisions: | Fakultas Kedokteran Gigi > Kedokteran Gigi |
| Depositing User: | soegeng sugeng |
| Date Deposited: | 10 Aug 2020 07:40 |
| Last Modified: | 23 Oct 2021 02:32 |
| URI: | http://repository.ub.ac.id/id/eprint/178896 |
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