Maulana, Nirwan (2019) Efek Preventif Infeksi Alami Protozoa Dengan Pemberian Ekstrak Daun Sambiloto Terhadap Aktivitas Enzim Gamma Glutamyl Transferase (Ggt) Hepar Dan Gambaran Vili Duodenum Kambing Peranakan Etawa. Sarjana thesis, Universitas Brawijaya.
Abstract
Protozoa adalah salah satu penyakit parasiter. Protozoa yang sering ditemukan di saluran pencernaan yaitu genus Eimeria.sp. Penelitian ini bertujuan untuk mengetahui efek ekstrak daun sambiloto (Andrographis Paniculata Nees) dapat mempengaruhi aktivitas enzim gamma glutamyl transferase (GGT) dan gambaran vili duodenum kambing peranakan etawa berumur 4 bulan dengan berat badan rata-rata 15 kg. penelitian ini menggunakan empat kelompok kambing yaitu kelompok control positif, perlakuan 1 (50mg/kgBB), perlakuan 2 (75mg/kgBB), perlakuan 3 (100mg/kgBB) diberikan per oral selama 27 hari. Analisa data dilakukan secara kuantitatif dengan One Way Analisis of Variance (ANOVA) dilanjutkan uji Tukey dengan α=0.05% untuk aktivitas GGT. Gambaran vili duodenum diamati secara deskriptif. Hasil menunjukkan bahwa pemberian ekstrak daun sambiloto dengan dosis 100mg/kgBB sangat signifikan (p<0,01) dapat menurunkan aktivitas enzim GGT sebesar 62,88% dari kontrol positif. Perbaikan gambaran vili duodenum ditunjukkan pada dosis 100mg/kgBB dengan diamati bentukan vili duodenum. Kesimpulan dari penelitian ini adalah terapi pemberian ekstrak daun sambiloto dapat mempengaruhi aktivitas enzim GGT, memperbaiki vili duodenum kambing peranakan etawa.
English Abstract
Protozoa is one of the cause of parasitic disease. Protozoa that were occasionally found at the digestive tract are Eimeria sp. This study was set to find the effects of green chiretta (Andrographis paniculata nees) leaves extract on Gamma Glutamyl Transferase (GGT) and duodenum villi illustration on a 4 months old etawa cross breed goats with the average weights of 15kg. This study used four groups of goats, control group and treatment group which were given 50 mg/kg BW, 75 mg/kg BW and 100 mg/kg BW PO green chiretta leaves extract for 27 days. Analysis of the GGT level used a quantitative study with One Way Analysis of Variance (ANOVA) then preceded Tukey test with α=0.05%. Duodenum villi then were analyzed descriptively. The results showed that green chiretta leaves extract with 100mg/kg BW dosage significantly (p>0.01) can lowered GGT level as much as 62,88% if compared to the positive group. The duodenum villi undergoes a recovery on the dosage of 100mg/kg BW which were observed from the duodenum villi images. The conclusion of this study are, therapeutic effects of green chiretta leaves extract can lower the GGT level and repair the duodenum villi on etawa crossbreed goats that were infected with protozoa.
Other obstract
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| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | SKR/FKH/2019/102/051909084 |
| Uncontrolled Keywords: | Protozoa, GGT, Duodenum, Peranakan Etawa, ANOVA, Protozoa, GGT, Duodenum, Etawa Cross Breed Goats, ANOVA |
| Subjects: | 600 Technology (Applied sciences) > 636 Animal husbandry > 636.3 Sheep and goats > 636.39 Goats > 636.390 85 Goats (Feeds and applied nutrition) > 636.390 852 Goats (Applied nutrition) |
| Divisions: | Fakultas Kedokteran Hewan > Kedokteran Hewan |
| Depositing User: | Nur Cholis |
| Date Deposited: | 02 Oct 2020 02:15 |
| Last Modified: | 21 Oct 2021 06:09 |
| URI: | http://repository.ub.ac.id/id/eprint/177032 |
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