Peter, Elijah Jayaraj (2018) Potential Antimicrobial Test Using Extract From Rosella (Hibiscus sabdariffa L.) Petals Against Salmonella Typhi Conducted in Vitro. Sarjana thesis, Universitas Brawijaya.
Abstract
Hibiscus sabdariffa L. atau umumnya dikenal sebagai rosela adalah tanaman berbunga yang berasal dari famili Malvaceae. Dalam sejarah pengobatan tradisional dan pengobatan alternatif rosela telah digunakan untuk menurunkan tekanan darah tinggi, menurunkan kolesterol, mencegah masalah jantung dan sebagai antioksidant. Rosela juga merupakan agen antibakteri. Penelitian ini dilakukan untuk membuktikan bahwa rosela memiliki efek antibakteri terhadap Salmonella Typhi, penyebab penyakit demam tifoid. Penelitian ini dilaksanakan di Laboratorium Mikrobiologi Fakultas Kedokteran, Universitas Brawijaya. Metode yang digunakan dalam penelitian ini adalah difusi sumuran dengan konsentrasi ekstrak 0%, 3,125%, 6,25%, 12,5%, 25%, 50% dan 100%. Data yang diperoleh dari Kruskal Wallis menginformasikan bahwa probabilitasnya <0,05, oleh karena itu dapat dinyatakan bahwa ada perbedaan yang signifikan dalam efek ekstrak rosela terhadap penghambatan pertumbuhan Salmonella Typhi. Uji korelasi Pearson menunjukkan koefisien sebesar 0,962, menunjukkan ada hubungan yang kuat antara rosela dengan Salmonella Typhi. Semakin tinggi konsentrasi ekstrak Hibiscus sabdariffa L., semakin tinggi tingkat penghambatan pertumbuhan Salmonella Typhi yang diamati. Penelitian ini membuktikan bahwa ekstrak rosela (Hibiscus sabdariffa L.) memiliki efek antibakteri terhadap pertumbuhan Salmonella Typhi secara in vitro.
English Abstract
Hibiscus Sabdariffa L. or generally known as rosella is a flowering plant that derive from the family Malvaceae family. In the history of traditional medicine and alternative treatment rosella had been used for lowering high blood pressure, lower cholesterol, prevent heart problems, as well as an antioxidant. It is also an antibacterial agent. This research is performed to prove rosella has an antibacterial effect towards Salmonella Typhi, which is often the cause of typhoid fever. This experiment was conducted at Laboratorium of microbiology, Faculty of Medicine, Brawijaya University. Method used in this research was Well’s diffusion with the different extract concentration of 0%, 3.125%, 6.25% 12.5%, 25%, 50% and 100%. The data obtained from Kruskal Wallis informs that the probability is < 0.05, therefore it can be stated that there is a significant different in the effect of rosella extract on the growth inhibition of Salmonella Typhi. The Pearson correlation test shows a coefficient of 0.962, indicating there is a strong relationship between rosella and Salmonella Typhi. The higher the concentration of Hibiscus sabdariffa L. extract, the higher the degree of growth inhibition of Salmonella Typhi observed. This research proves that rosella (Hibiscus sabdariffa L.) extract has an antibacterial effect towards the growth of Salmonella Typhi in vitro.
Other obstract
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| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | SKR/FK/2018/587/051804055 |
| Uncontrolled Keywords: | Hibiscus sabdariffa L., rosela, Salmonella Typhi, difusi sumuran, Hibiscus sabdariffa L., rosella, Salmonella Typhi, Well’s diffusion method. |
| Subjects: | 600 Technology (Applied sciences) > 616 Diseases > 616.9 Other disease > 616.929 7 Staphylococcal infections |
| Divisions: | Fakultas Kedokteran > Pendidikan Dokter |
| Depositing User: | Nur Cholis |
| Date Deposited: | 18 May 2020 07:43 |
| Last Modified: | 21 Oct 2021 04:48 |
| URI: | http://repository.ub.ac.id/id/eprint/167911 |
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