Efektivitas Ekstrak Kulit Pisang Kepok Kuning (Musa Paradisiaca L. Var Bluggoe) Sebagai Antibakteri Porphyromonas Gingivalis

Destyawati, Arum Anugrah (2018) Efektivitas Ekstrak Kulit Pisang Kepok Kuning (Musa Paradisiaca L. Var Bluggoe) Sebagai Antibakteri Porphyromonas Gingivalis. Sarjana thesis, Universitas Brawijaya.

Abstract

Penyakit periodontal dialami hampir 90% masyarakat di Indonesia. Periodontitis kronis adalah penyakit periodontal yang paling sering terjadi dengan mikroorganisme yang paling banyak adalah Porphyromonas gingivalis. Kulit pisang kepok kuning (Musa Paradisiaca L. Var. Bluggoe) memiliki kandungan flavonoid, tannin dan terpenoid yang mampu menghambat dan membunuh pertumbuhan Porphyromonas gingivalis. Tujuan: untuk membuktikan bahwa ekstrak kulit pisang kepok kuning (Musa paradisiaca L. var. bluggoe) efektif sebagai antibakteri Porphyromonas gingivalis. Metode: Penelitian ini adalah true eksperimental dengan pendekatan post test only control group. Sampel dibagi menjadi 2 kelompok kontrol dan 6 kelompok perlakukan (5%, 7.5%, 10%, 12.5%, 15%, 17.5%). Hasil: Kadar hambat Minimum (KHM) didapatkan hasil pada konsentrasi 10%. Kadar Bunuh minimum (KBM) ditentukan dengan menghitung jumlah koloni dan didapatkan pada konsentrasi 17,5%. Hasil uji statistika kekeruhan tabung menunjukkan terdapat perbedaan yang berarti pada setiap konsentrasi ekstrak (Kruskal wallis,p= 0,011), dan terdapat hubungan antara variabel konsentrasi dengan kekeruhan tabung (Spearman, correlation coeficient = 0,790). Hasil uji statistika pertumbuhan koloni menunjukkan terdapat perbedaan yang bermakna pada setiap konsentrasi ekstrak (Kruskal wallis, p=0,005), dan terdapat hubungan antara variabel konsentrasi dengan pertumbuhan koloni bakteri (Spearman, correlation coeficient = -0,977). Kesimpulan: Ekstrak kulit pisang kepok kuning (Musa paradisiaca L. var. bluggoe) efektif sebagai antibakteri Porphyromonas gingivalis.

English Abstract

The prevalence of Periodontal disease reach almost 90% in Indonesian community. Chronic periodontitis is the most common periodontal disease with the dominant microorganism is Porphyromonas gingivalis. The skin Kepok Kuning Banana contain flavonoid, tannin, and terpenoid which can inhibit and stop the growth of Porphyromonas gingivalis. Objectives: to know the Effect of Extract Skin Kepok Kuning Banana (Musa Paradisiaca L. Var. Bluggoe) As Antibacterial of Porphyromonas gingivalis. Methode: This study is true experimental with the post test only control group. The samples were divided into 2 groups, control, and 6 groups treatment (5%, 7.5%, 10%, 12.5%, 15%, 17.5%). Result: Minimum inhibitory concentration (MIC) at concentration of 10%. Minimum bactericidal consentration (MBC) was determined by counting using colony counter and the result of MBC is 17,5%. The statistical test result of tube turbidity showed a significant difference in each extract concentration (Kruskal wallis,p= 0,011), and there was a relationship between concentration variables with tube turbidity (Spearman, correlation coeficient = 0,790). The statistical test result of tube of Colony growth showed a significant difference in each extract concentration (Kruskal wallis,p= 0,005), and there was a relationship between concentration variables with the Colony growth (Spearman, correlation coeficient = -0,977). Conclusion: the extract Skin Kepok Kuning Banana (Musa Paradisiaca L. Var. Bluggoe) has effect As Antibacterial of Porphyromonas gingivalis.

Other obstract

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Item Type: Thesis (Sarjana)
Identification Number: SKR/FKG/2018/100/051900449
Uncontrolled Keywords: Kadar bunuh minimum, kadar hambat minimum, kulit pisang kepok kuning, Porphyromonas gingivalis. Minimum inhibitory concentration, minimum bactericidal consentration, skin lepok kuning banana, Porphyromonas gingivalis
Subjects: 600 Technology (Applied sciences) > 617 Surgery, regional medicine, dentistry, ophthalmology, otology, audiology > 617.6 Dentistry > 617.63 Dental diseases > 617.632 Diseases of gums and tooth sockets / Periodontics
Divisions: Fakultas Kedokteran Gigi > Kedokteran Gigi
Depositing User: Budi Wahyono Wahyono
Date Deposited: 25 May 2020 13:52
Last Modified: 22 Oct 2021 14:10
URI: http://repository.ub.ac.id/id/eprint/167867
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