Mursyidah, Azizah (2018) Pengaruh Rebusan Kulit Jeruk Nipis (Citrus aurantifolia s.) terhadap Ketebalan Epitel pada Luka Pasca Pencabutan Gigi Tikus Putih (Rattus norvegicus) Strain Wistas. Sarjana thesis, Universitas Brawijaya.
Abstract
Tindakan pencabutan gigi akan mengakibatkan kerusakan jaringan sekitar dan terjadi proses penyembuhan luka. Proses epitelisasi mempunyai peran penting dalam perbaikan jaringan yang terluka. Kulit jeruk nipis memiliki kandungan flavonoid. Tujuan penelitian ini adalah untuk mengetahui pengaruh rebusan kulit jeruk nipis (Citrus aurantifolia s.) terhadap ketebalan epitel pada luka pasca pencabutan gigi tikus putih (Rattus norvegicus) strain wistar. Penelitian ini dilakukan dengan pendekatan eksperimental laboratoris secara in vivo. Desain penelitian yang digunakan adalah Randomized Post-Test Only Control Group Design dimana subyek dibagi menjadi 6 kelompok, yaitu kelompok kontrol yang tidak diberi rebusan kulit jeruk nipis (K1, K2, K3) dan kelompok perlakuan yang diberi rebusan kulit jeruk nipis (P1, P2, P3) yang masing-masing didekaputasi pada hari ke-7, 14, 21 dan dibuat sediaan preparat histologi dengan pewarnaan HE untuk mengukur ketebalan epitel. Analisis data menggunakan One-Way Anova menunjukkan perbedaan yang bermakna antara kelompok kontrol dan kelompok perlakuan di hari ke-7, 14, 21. Uji korelasi Pearson menunjukkan adanya hubungan kuat dengan arah positif yang berarti semakin bertambahnya hari maka ketebalan epitel semakin meningkat. Berdasarkan penelitian ini, dapat disimpulkan bahwa rebusan kulit jeruk nipis berpengaruh terhadap ketebalan epitel pada luka pasca pencabutan gigi.
English Abstract
Tooth extraction will result in damage of surrounding tissues. Therefore, the process of wound healing occurs. The epithelialization process has an important role to the injured tissue repair. Lime zest contains flavonoids. The purpose of this study was to determine the effect of lime zest (Citrus aurantifolia s.) decoction on the epithelial thickness of wound healing after tooth extraction. This research was conducted with an experimental approach laboratoris in vivo. The research design used was the Randomized Post-Test Only Control Group Design in which subjects were divided into 6 groups: the control groups which were not given lime zest decoction (K1, K2, K3) and the treatment groups which were given lime zest decoction (P1, P2, P3), each sacrificed on the 7th, 14th, and 21st day, and later made into histology tissue preparations to measure the epithelial thickness. Data analysis using One-way Anova showed significant differences between the control group and the treatment group on the 7th, 14th, and 21st day. Pearson correlation test showed a strong relationship with positive direction which means that the the thickness of the epithelium progressively increases over time. Based on this research, it can be concluded that the decoction of lime zest has an impact to the epithelial thickness of wound healing after tooth extraction.
Other obstract
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| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | SKR/FKG/2018/48/051808340 |
| Uncontrolled Keywords: | Ketebalan epitel, kulit jeruk nipis (Citrus aurantifolia s.), pencabutan gigi Epithelial thickness, lime zest (Citrus aurantifolia s.), tooth extraction |
| Subjects: | 600 Technology (Applied sciences) > 615 Pharmacology and therapeutics > 615.3 Organics drugs > 615.32 Drugs derived from plants and mikroorganisms > 615.323 77 Drugs derived from spesific plants (Citrus) |
| Divisions: | Fakultas Kedokteran Gigi > Kedokteran Gigi |
| Depositing User: | Budi Wahyono Wahyono |
| Date Deposited: | 05 Jul 2019 03:16 |
| Last Modified: | 22 Oct 2021 13:10 |
| URI: | http://repository.ub.ac.id/id/eprint/167853 |
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