Lestari, Tri Kurnia (2018) Uji Daya Hambat Ekstrak Daun Belimbing Wuluh (Averrhoa bilimbi L.) terhadap Streptococcus pyogenes secara In Vitro. Sarjana thesis, Universitas Brawijaya.
Abstract
Streptococcus pyogenes merupakan salah satu mikroba patogen penyebab penyakit infeksi salah satunya pada manusia. Infeksi yang ditimbulkan oleh bakteri Streptococcus pyogenes ini dapat terjadi karena adanya interaksi faktor-faktor virulensi bakteri dengan sel host. Bakteri ini dapat menyebabkan berbagai macam penyakit, seperti faringitis, impetigo, erysipelas, demam purpura, scarlet fever. Tujuan dilakukan penelitian ini adalah untuk mengetahui efek pemberian antimikroba ekstrak daun belimbing wuluh (Averrhoa bilimbi L.) terhadap pertumbuhan bakteri Streptococcus pyogenes. Daun belimbing wuluh mengandung zat-zat aktif antara lain flavonoid, saponin, tanin, steroid/triterpenoid yang mempunyai kemampuan untuk menghambat pertumbuhan bakteri. Penelitian ini menggunakan rancangan eksperimental menggunakan difusi sumuran dengan konsentrasi ekstrak daun belimbing wuluh (Averrhoa bilimbi L) 0%, 3,125%, 6,25%, 12.5%, 25%, 50%, dan 100%. Berdasarkan hasil penelitian didapatkan zona hambat terkecil terbentuk pada konsentrasi 3,125% dengan diameter 6,5 mm sedangkan zona hambat terbesar pada konsentrasi 100% dengan diameter 18,6mm. Hasil uji statistik One-Way ANOVA didapatkan nilai yang signifikan sebesar 0,000 (p< 0,05) yang menunjukkan adanya perbedaan efek yang signifikan diantara ketujuh kelompok perlakuan. Berdasarkan hasil penelitian ini, dapat disimpulkan bahwa pemberian konsentrasi ekstrak daun belimbing wuluh memiliki efek yang signifikan dalam menghambat pertumbuhan bakteri Streptococcus pyogenes
English Abstract
Streptococcus pyogenes is one of pathogenic microbes that cause infectious diseases which also occurs in humans. Infection which caused by Streptococcus pyogenes bacteria can occur due to the interaction of bacterial virulence factors with host cells. These bacteria can cause various diseases, such as pharyngitis, impetigo, erysipelas, purpura fever, scarlet fever. The purpose of this study was to determine the effect of antimicrobial extract of starfruit leaves (Averrhoa bilimbi L.) on the growth of Streptococcus pyogenes bacteria. Starfruit leaves (Averrhoa bilimbi L.) contains active substances such as flavonoids, saponins, tannins, steroids / triterpenoids that have the ability to inhibit bacterial growth. This research used experimental design using disc diffusion test with concentration of starfruit leaves (Averrhoa bilimbi L) extract 0%, 3,125%, 6,25%, 12,5%, 25%, 50%, and 100%. Based on the research results obtained the smallest inhibition zone formed at concentrations of 3.125% with a diameter of 6.5 mm while the largest inhibition zone at 100% concentration with a diameter of 18.6mm. One-Way ANOVA statistical test results obtained a significant value of 0.000 (p <0.05) which showed a significant effect difference among the seven concentration groups. Based on the results of this study, it can be concluded that the concentration of starfruit leaves extract has a significant effect in inhibiting the growth of Streptococcus pyogenes bacteria.
Other obstract
-
| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | SKR/FK/2018/857/051804108 |
| Uncontrolled Keywords: | Streptococcus pyogenes, Belimbing Wuluh (Averrhoa bilimbi L.), efek antimikroba, Streptococcus pyogenes, Starfruit leaf (Averrhoa bilimbiL), antimicrobial effect |
| Subjects: | 600 Technology (Applied sciences) > 615 Pharmacology and therapeutics > 615.3 Organics drugs > 615.32 Drugs derived from plants and mikroorganisms > 615.323 79 Drugs derived from spesific plant (Oxalidaceae) |
| Divisions: | Fakultas Kedokteran > Pendidikan Dokter |
| Depositing User: | Nur Cholis |
| Date Deposited: | 16 Jul 2019 06:35 |
| Last Modified: | 21 Oct 2021 05:10 |
| URI: | http://repository.ub.ac.id/id/eprint/167673 |
Preview |
Text
Tri Kurnia Lestari.pdf Download (4MB) | Preview |
Actions (login required)
 |
View Item |