Dewanto, Bisma (2016) Hubungan Antara Ketebalan Carotid Intima-Media Dengan Volume Infark Pada Pasien Stroke Trombosis Akut. Sarjana thesis, Universitas Brawijaya.
Abstract
Stroke adalah penyebab utama kematian dini selain penyakit jantung koroner dan infeksi. Aterosklerosis adalah salah satu dari penyebab paling sering dari stroke. Aterosklerosis adalah suatu bentuk inflamasi yang terjadi pada dinding pembuluh darah. Aterosklerosis terbentuk saat ada akumulasi dari LDL yang mempromosikan agregrasi monosit dan berkembangnya foam cell. Pembentukan aterosklerosis pada arteri karotis, serebral dan koroner terjadi disaat yang hampir bersamaan. Penelitian ini bertujuan untuk menemukan korelasi antara carotid intima-media thickness (CIMT) dan volume infark pada pasien dengan stroke trombosis akut. CIMT diukur dengan menggunakan alat ultrasonography GE logiq s6 dengan probe linier (5-13 mhz) oleh 3 dokter radiologi di instalasi radiologi Rumah Sakit Umum dr. Saiful Anwar Malang. Volume infark di ukur dari hasil CT scan pasien saat di UGD menggunakan CT scan 16 slice. Formula yang digunakan adaah PxLxTx0,52. Data dianalisa menggunakan uji korelasi pearson. Didapatkan total 21 pasien dengan stroke trombosis akut. Penebalan CIMT didapatkan pada 90,48% pasien (1,209±0,297 mm). Volume infark juga diukur pada seluruh pasien (1045,780±865,018 mm3). Tidak didapatkan korelasi yang signifikan antara CIMT dan volume infark pada pasien dengan stroke trombosis akut (tes korelasi pearson, p=0,544, correlation=0,140). Disimpulkan bahwa tidak ada korelasi antara volume infark dengan CIMT pada pasien dengan stroke trombosis akut.
English Abstract
Stroke is a leading cause of premature death beside of coronary heart disease and infection. Atherosclerosis is one of the most frequent cause of stroke. Atherosclerosis is a form of inflammation that happened at vascular wall. Atherosclerosis are formed when there are accumulation of LDL that promote monocyte aggregration and development of foam cell. Atherosclerosis formation in carotid artery, cerebral and coronary happen at almost the same time. This cross sectional study is intended to find a correlation between carotid intima-media thickness (CIMT) and infarct volume in people with acute thrombotic stroke. CIMT was measured using ultrasonography GE Logiq S6 with linier probe (5-13 mhz) by 3 radiologist in radiology instalation of dr. Saiful Anwar General Hospital Malang. Infarct volume was measured from CT scan examination result during patient submission in emergency care unit using 16 slice CT scan. The measurement were conducted by measuring the largest diameter (P), the largest diameter perpendicular with the first diameter (L), the vertical diameter measured by summing the thickness of slice where the lesion were spotted (T). The formula is PxLxTx0,52. The data were analysized using pearson correlation. A total of 21 patients with acute thrombotic stroke were conducted. CIMT thickening was indicated in 90,48% patients (12,095±2,979 mm). Infarct volume was measured in all patient(1045,780±865,018 mm3). There were no significant correlation between CIMT and infarct volume in person with acute thrombotic stroke (Pearson correlation test, p=0,544, Correlation 0,140). We conclude that there are no correlation between infarct volume and CIMT in person with acute thrombotic stroke.
Item Type: | Thesis (Sarjana) |
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Identification Number: | SKR/FK/2016/770/051700390 |
Subjects: | 600 Technology (Applied sciences) > 610 Medicine and health > 610.7 Education, research, nursing, services of allied health personnel |
Divisions: | Fakultas Kedokteran > Pendidikan Dokter |
Depositing User: | Sugiantoro |
Date Deposited: | 01 Feb 2017 13:20 |
Last Modified: | 19 Oct 2021 03:54 |
URI: | http://repository.ub.ac.id/id/eprint/126482 |
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