JanuarMirhard, Fajar (2015) Uji Efektivitas Ekstrak Etanol Umbi Lobak (Raphanus sativus) Sebagai Antimikroba Terhadap Pertumbuhan Bakteri Streptococcus mutans Secara in Vitro. Sarjana thesis, Universitas Brawijaya.
Abstract
Infeksi rongga mulut sering disebabkan oleh bakteri Streptococcus mutans, bakteri ini juga merupakan salah satu bakteri yang berperan dalam infeksi saluran akar. Ekstrak lobak mempunyai kandungan zat aktif antibakteri yaitu flavonoid, tanin, saponin, dan polifenol. Tujuan penelitian untuk mengetahui efek ekstrak lobak sebagai anti bakteri terhadap Streptococcus mutans. Penelitian ini merupakan eksperimental laboratorik dengan metode dilusi agar untuk mendapatkan nilai KHM. Konsentrasi ekstrak etanol umbi lobak yang digunakan adalah 1%, 5%, 7,5%, 10%, 12,5% dan 15%. Hasil penelitian menunjukkan Kadar Hambat Minimum (KHM) diperoleh pada konsentrasi 15%. Analisis data menggunakan Post-Hoc Mann-Whitney menunjukkan adanya perbedaan yang signifikan pada perubahan konsentrasi ekstrak etanol umbi lobak terhadap jumlah koloni Streptococcus mutans (p<0,01). Uji korelasi Spearman menunjukkan adanya hubungan yang kuat dan berbanding terbalik antara konsentrasi ekstrak etanol umbi lobak dengan jumlah koloni Streptococcus mutans (-0,926). Berdasarkan penelitian ini, dapat disimpulkan bahwa ekstrak etanol umbi lobak mempunyai efek antibakteri terhadap Streptococcus mutans secara in vitro.
English Abstract
Intra oral infection usualy by Streptococcus mutans bacteria, its bacteria include to be one of root canal pathogen that caused root canal infection. Recent study show Indonesian radish ekstract by petroleum ether solvent contain flavonoid, tanin, saponin, and polifenol which has activity as antibacterial agent. The aim of this research is to know about efectivity of Indonesian radish ekstract by etanol solvent againt Streptococcus mutans.This is a laboratory experimental study using agar dilution method to find MIC. The used concentration of ethanolic extract of radish are 1%, 5%, 7,5%, 10%, 12,5% and 15%. The result shows the Minimum Inhibitory Concentration (MIC) is concentration of 15%. Analyzing post-hoc Mann-Whitney shows a significant difference in the change of concentration of ethanolic extract of radish on the number of colonies of Streptococcus mutans (p <0.01). Spearman correlation test shows a strong and inversely relationship between the concentration of ethanolic extract of radish and the number of colonies of Streptococcus mutans (-0,926). Based on this study, it can be concluded that the ethanolic extract of radish have antibacterial effects against Streptococcus mutans in vitro.
| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | SKR/FK/2015/289/051502178 |
| Subjects: | 600 Technology (Applied sciences) > 617 Surgery, regional medicine, dentistry, ophthalmology, otology, audiology > 617.6 Dentistry |
| Divisions: | Fakultas Kedokteran Gigi > Kedokteran Gigi |
| Depositing User: | Samsul Arifin |
| Date Deposited: | 13 Mar 2015 14:46 |
| Last Modified: | 19 Oct 2021 00:23 |
| URI: | http://repository.ub.ac.id/id/eprint/125047 |
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