Fitriana, Dinar Ika (2014) Hubungan Obesitas, Konsumsi Tinggi Purin, Dan Obat-Obatan Terhadap Kadar Asam Urat Pada Pasien Hiperurisemia Dengan Allopurinol (Penelitian Dilakukan di Instalasi Rawat Jalan Poli Ginjal Hipertensi Rumah Sakit Umum Daerah Dr. Saiful Anwar Malang). Sarjana thesis, Universitas Brawijaya.
Abstract
Hiperurisemia adalah keadaan meningkatnya kadar asam urat darah di atas normal. Beberapa faktor yang dapat meningkatkan kadar asam urat adalah obesitas, konsumsi tinggi purin dan obat-obatan. Penelitian ini bertujuan mengetahui hubungan obesitas, konsumsi tinggi purin, dan obat-obatan terhadap kadar asam urat pada pasien hiperurisemia dengan allopurinol. Pengambilan data melalui rekam medis dan kuesioner secara observasional yang menggunakan rancangan cross sectional. Data dianalisis secara deskriptif dan diuji hipotesis. Sampel adalah 45 pasien hiperurisemia yang mendapatkan terapi allopurinol minimal 1 bulan dan dipilih menggunakan metode consecutive sampling. Hasil penelitian menunjukkan bahwa tidak terdapat perbedaan yang signifikan secara statistik antara kadar asam urat terhadap obesitas, konsumsi tinggi purin (hasil laut, daging, jerohan, polong-polongan), dan obat-obatan (furosemid, aspirin dosis rendah, hidroklorotiazid, spironolakton) dengan nilai signifikansi berturut-turut 0,193; 0,420; 0,469; 0,054; 0,398; 0,631; 0,773; 0,216; 0,246. Selain itu, tidak terdapat korelasi yang signifikan secara statistik antara kadar asam urat terhadap obesitas, konsumsi tinggi purin (hasil laut, daging, jerohan, polong-polongan), dan obat-obatan (furosemid, aspirin dosis rendah, hidroklorotiazid, spironolakton) dengan nilai signifikansi berturut-turut 0,197; 0,426; 0,476; 0,053; 0,404; 0,637; 0,776; 0,220; 0,250. Kesimpulan dari penelitian ini, tidak terdapat perbedaan dan tidak terdapat korelasi yang signifikan secara statistik antara obesitas, konsumsi tinggi purin, dan obat-obatan terhadap kadar asam urat.
English Abstract
Hyperuricemia is the increasing of blood uric acid level. It exceeds normal amount. There were many factors that increase uric acid levels, such as obesity, high purine consumptions, and medications. The aim of this study is to determine the associations of obesity, high purine consumptions, and medications to uric acid levels in patients hyperuricemia with allopurinol. Data were collected through medical records and questionnaires with cross-sectional observational design. Data were analyzed descriptively and hypotheses test. The sample of this research is 45 hyperuricemia patient who have gotten allopurinol therapy for about a month and it were choosen by the consecutive sampling method. The result of this research shows that there were nothing significant comparative association statistically between uric acid levels on obesity, high purine consumptions (seafoods, meats, organ meats, pods), and medications (furosemide, low dose aspirin, hydrochlorotiazide, spironolacton) with consecutive significance values 0,193; 0,420; 0,469; 0,054; 0,398; 0,631; 0,773; 0,216; 0,246. Besides that, there were nothing significant correlation association statistically between uric acid levels on obesity, high purine consumptions (seafoods, meats, organ meats, pods), and medications (furosemide, low dose aspirin, hydrochlorotiazide, spironolacton) with consecutive significance values 0,197; 0,426; 0,476; 0,053; 0,404; 0,637; 0,776; 0,220; 0,250. The conclusion of this research were nothing significant comparative and nothing significant correlation between obesity, high purine consumptions, medications on uric acid levels
Other obstract
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| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | SKR/FK/2014/510/051403911 |
| Uncontrolled Keywords: | hiperurisemia, allopurinol, obesitas, makanan tinggi purin, obat-obatan; hyperuricemia, uric acid levels, allopurinol, obesity, high purine consumptions, medications |
| Subjects: | 600 Technology (Applied sciences) > 616 Diseases > 616.3 Diseases of digestive system > 616.39 Nutritional and metabolic diseases > 616.399 Other nutritional and metabolic diseases / Malnutrition |
| Divisions: | Fakultas Kedokteran > Farmasi |
| Depositing User: | Hasbi |
| Date Deposited: | 23 Jul 2014 09:01 |
| Last Modified: | 03 Dec 2021 16:22 |
| URI: | http://repository.ub.ac.id/id/eprint/124513 |
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