Uji Daya Anthelmintik Ekstrak Etanol Daun Kayu Putih (Melaleuca Leucadendron) Terhadap Ascaris Suum Secara In Vitro

Porsiana, MariaDiandra (2014) Uji Daya Anthelmintik Ekstrak Etanol Daun Kayu Putih (Melaleuca Leucadendron) Terhadap Ascaris Suum Secara In Vitro. Sarjana thesis, Universitas Brawijaya.

Abstract

Askariasis Merupakan Salah Satu Infeksi Cacing Terbanyak Di Indonesia Yangdisebabkan Oleh Cacing Ascaris Lumbricoides Yang Merupakan Nematoda Patogen Pada Usus Halus Yang Dapat Menyebabkan Malnutrisi, Gangguan Pertumbuhan, Gangguan Kognitif, Dan Obstruksi Saluran Pencernaan. Dengan Adanya Efek Samping Dan Harga Yang Mahal Pada Obat Anthelmintik Konvensional, Maka Perlu Dilakukannya Evaluasi Terhadap Tanaman Obat Sebagai Alternatif Obat Anthelmintik. Tujuan Dari Penelitian Ini Adalah Untuk Mengetahui Daya Anthelmintik Dari Ekstrak Daun Kayu Putih ( Melaleuca Leucadendron ) Terhadap Cacing Ascaris Suum Secara In Vitro dan Untuk Mengetahui Lethal Time (LT100) Dan Lethal Concentration (LC100) Dari Ekstrak Etanol Daun Kayu Putih. Penelitian Ini Merupakan Penelitian Eksperimental Laboratorium Dengan Rancangan Penelitian Post Test Only Control Group Design . S Ubjek Dari Penelitian Ini Adalah Cacing ascaris Suum Yang Didapat Dari Rumah Pemotongan Hewan Gadang. Penelitian Ini Menggunakan 5 Kelompok Perlakuan Yaitu Nacl 0,996 Sebagai Kontrol Negatif Dan Pirantel Pamoate 1% Sebagai Kontrol Positif Serta Ekstrak Daun Kayu Putih ( Melaleuca Leucadendron ) Dengan Konsentrasi 2096, 3096, Dan 4096. Data Yang Diperoleh Diuji Secara Statistik Dengan Analisis Probit Untuk Mengetahui Lethal Concentration (LC100) Dan Lethal Time 100 (LT100) Dari Ekstrak Etanol Daun Kayu Putih ( Melaleuca Leucadendron ). Hasil Ujinormalitas Menunjukkan Distribusi Normal (P> 0,05). Hasil Analisis Probitmenunjukkan Lethal Concentration 100 (LC100) Ekstrak Etanol Daun Kayu Putih( Melaleuca Leucadendron ) Adalah 39,896 Sedangkan Lethal Time 100 (LT100) Padakonsentrasi 4096 Adalah 15 Jam 58 Menit. Dari Penelitian Ini Dapat Disimpulkan Bahwa Ekstrak Etanol Daun Kayu Putih ( Melaleuca Leucadendron ) Memiliki Daya

English Abstract

Ascariasis Is One Of The Most Common Human Helminthic Infections In Indonesia Caused By Ascaris Lumbricoides Which Is The Highly Pathogenic Nematode Parasite Of Small Intestine Causing Malnutrition, Growth And Cognitive Disorder, And Digestive Tract Obstruction. The Presence Of Adverse Effect And High Cost Of Conventional Anthelmintic Drugs Led To The Evaluation Of Medicinal Plants As An Alternative Of Anthelmintic Drugs. The Aim Of This Study Was To Investigate Theethanol Extract Of Eucalyptus Leaves ( Melaleuca Leucadendron ) As An Anthelmintic Againts Ascaris Suum In Vitro, And To Identify Lethal Time 100 (LT100) And Lethal Concentration 100 (LC100) Toward Ethanol Extract Of Eucalyptus Leaves ( Melaleuca Leucadendron ). This Study Was An Experimental Laboratory With Post Only Controlled Group Design. The Research Subject Was Actively Living Ascarissuum , Which Were Obtained From A Slaughter House In Gadang. Samples Were Divided Into Five Treatment Groups, There Were Negative Control (0.996 Nacl), Positive Control (0.1% Pirantel Pamoate), And The Treatment Group With Concentration Of 2096, 3096 And 4096, Respectively. The Data Were Statistically Tested With The Probit Analysis In Order To Know Lethal Concentration 100 (LC100) And Lethal Time 100 (LT100) Toward Ethanol Extract Of Eucalyptus Leaves ( Melaleuca Leucadendron) . The Result Of Normality Test Shown Normal Distribution (P>0.05). The Result Of Probit Analysis Shown That The Lethal Concentration 100 (LC100) Of Ethanol Extract Of Eucalyptus Leaves ( Melaleuca Leucadendron) Was 39,8% While The Lethal Time 100 (LT100) In 4096 Leaves Extract Was 15 Hours 58 Minutes. It Was Concluded That Ethanol Extract Of Eucalyptus Leaves ( Melaleucaleucadendron ) Has The Effect Of Anthelmintic Againts Ascaris Suum In Vitro

Item Type: Thesis (Sarjana)
Identification Number: SKR/FK/2014/175/051402179
Subjects: 600 Technology (Applied sciences) > 610 Medicine and health > 610.7 Education, research, nursing, services of allied health personnel
Divisions: Fakultas Kedokteran > Pendidikan Dokter
Depositing User: Budi Wahyono Wahyono
Date Deposited: 28 Mar 2014 08:42
Last Modified: 21 Oct 2021 07:55
URI: http://repository.ub.ac.id/id/eprint/124145
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