Pratiwi, Armeida (2017) Analisis Kandungan Zingeron Pada Formulasi Minuman Fungsional Berbahan Dasar Jahe Dan Kacang-Kacangan Sebagai Antiemetik Pada Ibu Hamil. Sarjana thesis, Universitas Brawijaya.
Abstract
Kejadian mual muntah pada wanita hamil tergolong cukup tinggi yaitu berkisar 50-90%. Hal tersebut disebabkan karena peningkatan radikal bebas Nitrit Oksida (NO) dan pelepasan neurotransmitter (serotonin) yang dapat merangsang pusat muntah di sistem saraf pusat. Minuman fungsional ini terdiri dari bahan utama jahe yang mengandung senyawa antioksidan zingeron yang berfungsi sebagai penangkap radikal bebas Nitrit Oksida (NO) dan penghambat input saraf aferen visceral dengan bertindak sebagai antagonis reseptor 5-HT3. Namun, zingeron dapat terbentuk apabila senyawa gingerol pada jahe berdekomposisi pada suhu tinggi. Tujuan penelitian ini adalah untuk mengetahui adanya kandungan zingeron pada beberapa formulasi minuman fungsional berbahan dasar jahe dan kacang-kacangan. Jenis penelitian yang digunakan yaitu eksperimental nyata. Penelitian ini menggunakan 3 formulasi terbaik minuman fungsional berbahan dasar jahe dan kacang-kacangan dengan proporsi sari jahe : kedelai : kacang hijau berturut-turut yaitu 22,24% : 31,78% : 45,98% pada formula 1, 17,25% : 32,75% : 50,00% pada formula 2, dan 33,35% : 20,00% : 46,65% pada formula 3 yang didapatkan dari hasil optimasi software Design Expert 7.0. Kandungan zingeron diuji dengan metode GCMS (Gas Chromatography Mass Spectrofotometry) dan didapatkan hasil kandungan zingeron pada formula 1 hingga formula 3 yaitu 12,98%; 3,15%, dan 13,93%. Kesimpulan dari penelitian ini yaitu terdapat kandungan zingeron pada 3 formulasi minuman fungsional berbahan dasar jahe dan kacang-kacangan. Kandungan tertinggi ada pada formulasi 3 dengan proporsi sari jahe 33,351%.
English Abstract
The incidence of nausea and vomiting in pregnant women is quite high, ranging from 50-90%. One of those many factors is due to the increasing of free radicals of Nitric Oxide (NO) and releasing of neurotransmitters (serotonin) that can affect the central nausea in the central nervous system. This functional drinks contains of zingeron antioxidant that serves as a scavenger of free radical Nitric Oxide (NO) and input inhibitor of visceral afferent by acting as a 5-HT3 receptor antagonist. However, zingeron can be formed by decomposition of gingerol at high temperatures. The purpose of this study was to determine the existence of zingeron compound in some formulation of functional drinks made from ginger and nuts. The type of this research was true experimental study. This research using best 3 formulation of functional drinks with proportion of ginger extract: soybeans extract: mung beans extract respectively is 22.24%: 31.78%: 45.98% on first formula; 17.25%: 32.75%: 50.00% on second formula; and 33.35%: 20.00%: 46.65% on third formula from optimization result of Design Expert 7.0. Zingeron compound was analyzed using GCMS (Gas Chromatography Mass Spectrophotometry) and the results of zingeron compound on the first to third formula were 12.98%, 3.15%, and 13.93%. The conclusion is zingeron compound is available in three formulations of functional drinks. The highest content is in the third formulation with ginger extract ratio 33.351%.
| Item Type: | Thesis (Sarjana) |
|---|---|
| Identification Number: | SKR/FK/2017/328/051705941 |
| Uncontrolled Keywords: | minuman fungsional, jahe, zingeron, antiemetik |
| Subjects: | 600 Technology (Applied sciences) > 615 Pharmacology and therapeutics > 615.3 Organics drugs > 615.32 Drugs derived from plants and mikroorganisms > 615.324 39 Drugs derived from specific plants (Ginger, Musaceae, Zingiberales) |
| Divisions: | Fakultas Kedokteran > Ilmu Gizi |
| Depositing User: | Kustati |
| Date Deposited: | 08 Aug 2017 06:36 |
| Last Modified: | 13 Oct 2020 02:55 |
| URI: | http://repository.ub.ac.id/id/eprint/1121 |
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